The change mechanism and rule of transducer driving electric power in high intensity focused ultrasound therapy
The driving electric power in high-intensity focused ultrasound(HIFU)treatment plays a crucial role in treatment efficiency,and the accuracy of driving electric power control inevitably affect the efficiency and safety of treatment.Previous studies show that changes in the transient physical characteristics of the focal region during HIFU treatment can lead to changes in the load impedance of the transducer,thereby affecting the driving electric power output of HIFU.However,the relationship and pattern between the driving electric power and the transient physical characteristics of the focal region are not yet clear.This article constructs a real-time monitoring system for driving electric power and focal domain acoustic cavitation and temperature detection in HIFU treatment based on devices such as voltage and current sensors,cavitation detection probes,and temperature sensors.Based on this experimental research system,in vitro bovine heart tissue is used as the HIFU irradiation object to study the relationship and rules between the changes in focal region temperature,acoustic cavitation,tissue damage,and driving electric power of HIFU.The research results indicate that as the focal region temperature increases,the driving electric power slowly increases,and there is a good correlation between the driving electric power and temperature changes;When cavitation occurs,there is a significant fluctuation in the driving electric power;when tissue damage occurs,the driving electric power shows a sudden decrease in change.Under the three scenarios,there are significant differences in the changes in driving electric power,which is expected to provide a new solution for distinguishing between damage and cavitation in the focal region during HIFU treatment,as well as real-time monitoring of the degree of target tissue damage.
High intensity focused ultrasoundDriving electric powerTissue damageTemperatureAcoustic cavitation
万方数据
维普
