Transmission enhancement analysis of transcranial ultrasound system based on transfer matrix method
The transcranial ultrasound technology has great potential in the field of intracranial imaging,neu-romodulation,intracranial tumor ablation,etc.However,the transcranial ultrasound technology is still limited in clinic since the large impedance mismatch between the transducer,water and skull inducing most acous-tic wave cannot transmit into brain.Here,we investigate the ultrasound propagation in the one-dimensional transcranial ultrasound system by using the transfer matrix method.We found that by adding a material with the same acoustic impedance of the skull on the external surface of the skull and adjusting its thickness,the transmission coefficient of transcranial ultrasound system can reach to 100%at the target frequency.The thickness of the water between the transducer and skull does not affect the transmission coefficient.This work paves the way for the enhancement of the transmission efficiency of the transcranial ultrasound system.