脑组织热-力耦合行为综述
A Review of Coupled Thermo-Mechanical Behaviors of Brain Tissue
秦璇 1苏丽君 1万秀伟 1陶泽 1孙学超 1卢天健1
作者信息
- 1. 南京航空航天大学 航空航天结构力学及控制全国重点实验室,南京 210016;南京航空航天大学 多功能轻量化材料与结构工信部重点实验室,南京 210016
- 折叠
摘要
脑组织是由固相与液相组成的饱和含液多孔材料,固、液、生理环境(尤其温度)之间相互作用,具体表现为脑组织内部温度场、渗流场、应力场相互影响的热-力耦合行为,故阐明脑组织的热-力耦合行为是理解大脑功能和疾病病理的关键.该文首先介绍了脑组织的传热学和力学性质,重点关注实验测量及应变率和温度的影响;其次,总结了描述脑组织热-力耦合行为的数理模型,包括力学模型、传热学模型和热-力耦合模型;最后,对该重要学科交叉领域进行了总结和展望.
Abstract
The brain is the highest nerve center regulating physiological behaviors and functions.Brain tissue is a saturated porous material composed mainly of solid phase and liquid phase.Interactions between the solid phase,the liquid phase and the physiological environment(temperature in particular)are manifested in the coupled thermo-mechanical behaviors of brain tissue,and affected by internal temperature,seepage and stress fields.Characterization of the coupled thermo-mechanical behaviors of brain tissue is the key to understanding brain function and disease pathology.Firstly,the thermal and mechanical properties of brain tissue measured via different experimental methods were introduced,with a particular focus placed upon the effects of the strain rate and the temperature.Theoretical and numerical models describing the coupled thermo-mechanical behaviors of brain tissues were then summarized,including mechanical models,heat transfer models and cou-pled thermo-mechanical models.Finally,this important multidisciplinary field was summarized and prospected.
关键词
脑组织/力学性质/热物性/热-力耦合Key words
brain tissue/mechanical property/thermophysical property/thermo-mechanical coupling引用本文复制引用
基金项目
国家自然科学基金(12032010)
江苏省研究生科研与实践创新计划(KYCX24_0543)
江苏省研究生科研与实践创新计划(KYCX24_0535)
出版年
2024
国家科技期刊平台
NSTL
万方数据