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胎盘早剥患者产后出血发生率及其影响因素分析

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目的 探讨胎盘早剥患者产后出血(PPH)的影响因素。方法 回顾性分析 2020 年 6 月至 2022 年 7 月上蔡县人民医院收治的 182 例胎盘早剥患者临床资料,统计PPH发生率,将其分为发生PPH患者组与未发生PPH患者组,其中确诊患者纳入发生PPH患者组,未确诊患者纳入未发生PPH患者组,并统计患者基本信息,经单因素和多因素分析明确胎盘早剥患者PPH的影响因素。结果 182例胎盘早剥患者,发生PPH 29例,占比15。93%;未发生PPH 153例,占比 84。07%。发生PPH患者的胎盘早剥位置、胎盘早剥严重程度、血清D-二聚体(D-D)水平、胎盘粘连及子宫收缩乏力情况与未发生PPH患者相比,差异有统计学意义(P<0。05)。两组间年龄、孕周、孕次组间比较,差异无统计学意义(P>0。05)。经Logistic回归分析,后壁胎盘早剥、胎盘早剥严重程度为Ⅲ度、血清D-D水平≥2 mg/L、胎盘粘连及子宫收缩乏力是胎盘早剥患者发生PPH的独立危险因素,差异有统计学意义(OR>1,P<0。05)。发生PPH患者新生儿窒息、子宫卒中、围产期弥散性血管内凝血、子宫切除发生率高于未发生PPH患者,差异有统计学意义(P>0。05)。结论 胎盘早剥患者发生PPH风险较大,且后壁胎盘早剥、胎盘早剥Ⅲ度、血清D-D水平高、胎盘粘连及子宫收缩乏力等是胎盘早剥患者发生PPH的影响因素,PPH可增加母婴不良结局风险,临床应据此进行合理产前干预,以降低PPH发生风险。
Analysis of the Incidence and influencing Factors of postpartum Hemorrhage in Patients with placental Abruption
Objective To explore the influencing factors of postpartum hemorrhage(PPH)in patients with placental abruption.Methods A retrospective analysis was conducted on the clinical data of 182 patients with placental abruption admitted to Shangcai County People's Hospital from June 2020 to July 2022.The incidence of PPH was calculated and divided into two groups:PPH group,non-PPH group.Confirmed patients were included in the group of patients with PPH,while those without PPH were included in the group of patients without PPH.Basic patient information was also collected,and the influencing factors of PPH in patients with placental abruption were identified through univariate and multivariate analysis.Results Among 182 patients with placental abruption,29 cases(15.93%)developed PPH;153 cases of PPH did not occur,accounting for 84.07%.There were statistically significant differences(P<0.05)in the location and severity of placental abruption,serum D-dimer(D-D)levels,placental adhesions,and uterine contractions between patients with PPH and those without PPH.There was no statistically significant difference in age,gestational age,and gestational frequency between the two groups(P>0.05).Logistic regression analysis showed that posterior placental abruption,severity of placental abruption at gradeⅢ,serum D-D level≥2 mg/L,placental adhesion,and uterine atony were independent risk factors for PPH in patients with placental abruption,with statistically significant differences(OR>1,P<0.05).The incidence of neonatal asphyxia,uterine stroke,perinatal disseminated intravascular coagulation,and hysterectomy in patients with PPH was higher than that in patients without PPH,and the difference was statistically significant(P>0.05).Conclusion Patients with placental abruption have a higher risk of developing PPH,and factors such as posterior wall placental abruption,grade Ⅲ placental abruption,high serum D-D levels,placental adhesions,and uterine contractions are the influencing factors for PPH in placental abruption patients.PPH can increase the risk of adverse maternal and infant outcomes,and reasonable prenatal interventions should be carried out based on this to reduce the risk of PPH.

placental abruptionpostpartum hemorrhageD-dimer

翟倩岚

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上蔡县人民医院 妇产科,河南 驻马店 463800

胎盘早剥 产后出血 D-二聚体

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(1)
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