The Incidence and influencing Factors of left ventricular Thrombosis after PCI in Patients with acute ST-segment Elevation myocardial Infarction
Objective To analyze the influencing factors of left ventricular thrombosis(LVT)in patients with acute ST-segment elevation myocardial infarction(STEMI)after PCI treatment.Methods A retrospective analysis was conducted on the case data of 116 STEMI patients who received treatment at the Second People's Hospital of Lingbao City from June 2019 to June 2021.Based on the incidence of LVT within 3 months of postoperative follow-up,the 116 patients were divided into incidence group and non-incidence group.General clinical data and testing indicators for two groups of patients were collected,including blood glucose(BG),glycated hemoglobin(GHb),total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),D-dimer(D-D),cardiac troponin(cTnT),creatine kinase MB(CK-MB),platelet count(PLT),white blood cell(WBC),and uric acid(UA).Logistic regression was used to analyze the influencing factors of LVT occurrence after PCI in patients with STEMI.Results A total of 116 STEMI patients who received PCI treatment were counted,among which 12 patients(10.34%)developed LVT within 3 months of postoperative follow-up.There were 104 patients without LVT,accounting for 89.66%.The left ventricular ejection fraction(LVET)of the incidence group was lower than that of the non-incidence group,and the proportion of TIMI grade 1 was higher than that of the non-incidence group,with a statistically significant difference(P<0.05).The expression of whole blood WBC,plasma D-D,and UA in the incidence group was higher than that in the non-incidence group,and the difference was statistically significant(P<0.05).The data from constructing a logistic regression model showed that TIMI level 1,plasma D-D,whole blood WBC,high UA expression,and decreased LVEF were the influencing factors for the occurrence of LVT in STEMI patients after PCI,and the differences were statistically significant(OR>1,P<0.05).Conclusion The incidence of LVT in STEMI patients after PCI is higher.TIMI grade 1,plasma D-D,whole blood WBC,high expression of UA,and decreased LVEF can all increase the risk of LVT in STEMI patients after PCI.