首页|急性ST段抬高型心肌梗死患者PCI术后左心室血栓发生状况及其影响因素

急性ST段抬高型心肌梗死患者PCI术后左心室血栓发生状况及其影响因素

扫码查看
目的 分析急性ST段抬高型心肌梗死(STEMI)患者PCI治疗后发生左心室血栓(LVT)的影响因素。方法 收集2019年6月至2021年6月在灵宝市第二人民医院接受诊治的116例STEMI患者病例资料进行回顾性分析,根据术后随访 3 个月内LVT发生情况将 116 例患者分为发生组和未发生组。统计两组患者一般临床资料及检测指标,包括血糖(BG)、糖化血红蛋白(GHb)、总胆固醇(TC)、三酰甘油(TG)、高密度蛋白总胆固醇(HDL-C)、低密度蛋白总胆固醇(LDL-C),D-二聚体(D-D),肌钙蛋白(cTnT)、肌酸激酶(CK-MB),血小板计数(PLT),白细胞(WBC),尿酸(UA),采用Logistic回归,分析STEMI患者PCI术后LVT发生的影响因素。结果 共统计 116 例接受过PCI治疗的STEMI患者,其中术后随访 3 个月内发生LVT患者 12 例(10。34%)。未发生LVT患者共 104 例,占 89。66%。发生组左心室射血分数(LVET)低于未发生组,TIMI 1 级占比多于未发生组,差异有统计学意义(P<0。05)。发生组全血WBC、血浆D-D,UA表达均高于未发生组,差异有统计学意义(P<0。05)。构建Logistic回归模型数据显示,TIMI 1 级、血浆D-D、全血WBC、UA高表达、LVEF降低是STEMI患者PCI术后发生LVT的影响因素,差异有统计学意义(OR>1,P<0。05)。结论 STEMI患者PCI术后LVT的发生率较高,TIMI 1 级、血浆D-D、全血WBC、UA高表达、LVEF降低均可增加STEMI患者PCI术后LVT的发生风险。
The Incidence and influencing Factors of left ventricular Thrombosis after PCI in Patients with acute ST-segment Elevation myocardial Infarction
Objective To analyze the influencing factors of left ventricular thrombosis(LVT)in patients with acute ST-segment elevation myocardial infarction(STEMI)after PCI treatment.Methods A retrospective analysis was conducted on the case data of 116 STEMI patients who received treatment at the Second People's Hospital of Lingbao City from June 2019 to June 2021.Based on the incidence of LVT within 3 months of postoperative follow-up,the 116 patients were divided into incidence group and non-incidence group.General clinical data and testing indicators for two groups of patients were collected,including blood glucose(BG),glycated hemoglobin(GHb),total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),D-dimer(D-D),cardiac troponin(cTnT),creatine kinase MB(CK-MB),platelet count(PLT),white blood cell(WBC),and uric acid(UA).Logistic regression was used to analyze the influencing factors of LVT occurrence after PCI in patients with STEMI.Results A total of 116 STEMI patients who received PCI treatment were counted,among which 12 patients(10.34%)developed LVT within 3 months of postoperative follow-up.There were 104 patients without LVT,accounting for 89.66%.The left ventricular ejection fraction(LVET)of the incidence group was lower than that of the non-incidence group,and the proportion of TIMI grade 1 was higher than that of the non-incidence group,with a statistically significant difference(P<0.05).The expression of whole blood WBC,plasma D-D,and UA in the incidence group was higher than that in the non-incidence group,and the difference was statistically significant(P<0.05).The data from constructing a logistic regression model showed that TIMI level 1,plasma D-D,whole blood WBC,high UA expression,and decreased LVEF were the influencing factors for the occurrence of LVT in STEMI patients after PCI,and the differences were statistically significant(OR>1,P<0.05).Conclusion The incidence of LVT in STEMI patients after PCI is higher.TIMI grade 1,plasma D-D,whole blood WBC,high expression of UA,and decreased LVEF can all increase the risk of LVT in STEMI patients after PCI.

acute ST-segment elevation myocardial infarctionpercutaneous coronary interventionleft ventricular thrombosisleft ventricular ejection fractionTIMI blood flow classification

金鑫

展开 >

灵宝市第二人民医院 心血管内科,河南 三门峡 472500

急性ST段抬高型心肌梗死 经皮冠状动脉介入术 左心室血栓 左心室射血分数 TIMI血流分级

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(1)
  • 21