The Diagnostic Value of 4D Ultrasound Combined with MRI for Fetal Spina Bifida Occulta Authors
Objective To explore the diagnostic value of prenatal 4D ultrasound combined with Magnetic Resonance Imaging(MRI)for fetal Spina Bifida Occulta(SBO).Methods A retrospective analysis was conducted on the clinical data of 98 pregnant women who underwent prenatal examinations in the General Hospital of Jinshui District,Zhengzhou from May 2019 to November 2021 and were suspected of having fetal spina bifida.All pregnant women underwent 4D ultrasound and MRI examinations.The results after induction or delivery were used as the"gold standard"to compare the effect of 4D ultrasound combined with MRI in diagnosing fetal SBO and predict the diagnostic efficiency with the Receiver Operating Characteristic(ROC)curve.Results Among the 98 pregnant women suspected of having fetal SBO,the"gold standard"diagnostic results showed a total of 13 cases of SBO.4D ultrasound correctly diagnosed 9 cases of SBO,MRI correctly diagnosed 10 cases of SBO,and the combined diagnosis identified 13 cases of SBO.Compared with the"gold standard"diagnosis of SBO,both 4D ultrasound and MRI showed good consistency(Kappa=0.679,Kappa=0.667,P＜0.05),while the combined diagnosis showed excellent consistency(Kappa=0.957,P＜0.05).In addition,the sensitivity of the combined diagnosis of SBO was higher than that of 4D ultrasound;the accuracy of the combined diagnosis of SBO was higher than that of 4D ultrasound and MRI alone.ROC curve analysis showed that the area under the curve(AUC)of 4D ultrasound combined with MRI in diagnosing SBO was higher than that of 4D ultrasound and MRI alone.Conclusion The combined use of 4D ultrasound and MRI can improve the accuracy of prenatal diagnosis of fetal SBO.
国家科技期刊平台
NSTL
万方数据
维普
