Diagnostic Value of Cervical Ultrasound Elastography Combined with Contrast-enhanced Ultrasound for Carotid Atherosclerosis in Cerebral Infarction
Objective To evaluate the diagnostic value of cervical ultrasound elastography combined with contrast-enhanced ultrasound in carotid atherosclerosis(CAS)in cerebral infarction.Methods A total of 320 patients with cerebral infarction admitted to the Seventh People's Hospital of Zhengzhou from October 2021 to October 2022 were selected for routine ultrasound,neck ultrasound elastography,and contra-ultrasound examination,with digital subtraction angiography as the gold standard.The plaque detection rate,stability and instability,plaque detection parameters,and diagnostic value were compared.Results A total of 251 CAS plaques(78.44%)were detected in 320 patients with cerebral infarction.The detection rate of CAS plaque by neck ultrasound elastography combined with contrast-enhanced ultrasound(98.41%)was higher than that by conventional ultrasound(87.65%),neck ultrasound elastography(94.42%),and contrast-enhanced ultrasound(94.82%).The detection rate of soft plaque of cervical ultrasound elastography combined with contrast-enhanced ultrasound and contrast-enhanced ultrasound(98.11%,95.60%)was higher than that of conventional ultrasound and cervical ultrasound elastography(86.16%,89.31%).The detection rate of neck ultrasound elastography combined with contrast-enhanced ultrasound(97.22%)was significantly higher than that of conventional ultrasound(77.78%).The patch thickness,elasticity score,and enhancement density of the stable patch group were lower than those of the unstable patch group.The AUC of plaque thickness,elasticity score,and enhancement density for single and combined diagnosis of CAS unstable plaques in cerebral infarction were 0.888,0.973,0.774,and 0.995,respectively,indicating that the sensitivity and specificity of combined diagnosis were higher,and the difference was statistically significant(P<0.05).Conclusion Conventional ultrasound,neck ultrasound elastic imaging and contrast ultrasound can diagnose CAS in cerebral infarction.Meanwhile,plaque thickness,elastic score,and enhanced density can effectively evaluate the stability of CAS plaques in cerebral infarction,and the combined diagnosis value is higher.