Application Value of CT Perfusion Imaging and CT Enhancement Examination in Patients Undergoing Brain glioma Surgery
Objective To explore the application value of CT perfusion imaging and CT enhancement examination in patients undergoing brain glioma surgery.Methods A total of 98 patients undergoing brain glioma surgery the First People's Hospital of Xinxiang City were retrospectively analyzed between January 2021 and December 2022.According to different examination methods,they were divided into CT perfusion group(n=52)and CT enhancement group(n=46).Taking the pathological examination report after surgical resection as the gold standard,application value of the above two detection methods in patients undergoing brain glioma surgery was analyzed.Results Among the 24 low-grade patients diagnosed with CT perfusion and 28 high-grade patients diagnosed with CT perfusion,there was no significant difference in cerebral blood flow(CBF)and cerebral blood volume(CBV)on healthy side between low-grade group and high-grade group(P＞0.05),but CBF and CBV of lesion area in high-grade group were significantly higher than those in low-grade group,and the difference was statistically significant(P＜0.05).Among the 21 low-grade patients and 25 high-grade patients in CT enhancement group,there was no significant difference in CT enhancement value on healthy side between low-grade group and high-grade group(P＞0.05),but CT enhancement value of lesion area in high-grade group was significantly greater than that in low-grade group,and the difference was statistically significant(P＜0.05).The sensitivity,specificity and accuracy of CT perfusion were 96%,100%,96.15%,1.00 positive predictive value,0.5 negative predictive value and 0.649 Kappa value in the diagnosis of glioma patients.The sensitivity,specificity and accuracy of enhanced CT were 52.50%,100%,58.70%,1.00 positive predictive value and 0.24 negative predictive value in the diagnosis of glioma.The Kappa value was 0.224.The diagnostic accuracy of CT perfusion group was higher than that of CT enhancement group.Conclusion CT perfusion imaging is beneficial to improve diagnostic accuracy of preoperative grading.However,there are statistical differences between different levels of CT perfusion and CT enhancement parameters,which have certain reference value for the risk assessment of malignant glioma lesions.
brain gliomaCT perfusion imagingCT enhancement examinationapplication value
国家科技期刊平台
NSTL
万方数据
维普
