Application Effect of early Liquid Management combined with enteral Nutrition Support in acute respiratory Distress Syndrome
Objective To explore the application effect of early fluid management combined with enteral nutrition support in acute respiratory distress syndrome.Methods A total of 84 patients with respiratory distress syndrome who received treatment at Anyang People's Hospital from March 2020 to March 2022 were selected.They were randomly divided into control group(liquid management + conventional treatment)and observation group(liquid management + enteral nutrition support)using a random number table method,with 42 cases in each group.Clinical indicators,inflammatory factors,nutritional indicators,blood gas indicators,and immune indicators were compared between the two groups.Results The mechanical ventilation time,hospitalization time,and mortality rate of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,both groups showed a decrease in inflammatory factors,while the observation group had lower levels of interleukin-1(IL-1),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)than those of the control group,and the difference was statistically significant(P＜0.05).After treatment,the nutritional indicators of both groups increased,and the levels of transferrin(TRF),albumin(ALB),and prealbumin(PAB)in the observation group were higher than those in the control group,with statistical significance(P＜0.05).After treatment,the pH and partial pressure of blood oxygen(PaO2)increased and partial pressure of blood carbon dioxide(PaCO2)decreased in both groups.The observation group had higher pH and PaO2 than those in the control group,while PaCO2 was lower than that in the control group,with statistically significant differences(P＜0.05).After treatment,the immune function indicators of both groups increased.The observation group had higher levels of immunoglobulin A(IgA),immunoglobulin G(IgG),and immunoglobulin M(IgM)compared to those in the control group,with statistical significance(P＜0.05).Conclusion Early fluid management combined with nutritional support can improve blood gas indicators,promote protein synthesis,enhance immune function,and reduce inflammatory factors in patients with acute respiratory distress syndrome.
early liquid managemententeral nutrition supportacute respiratory distress syndromeinflammatory factorsimmunologic function
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