Impacts of Low Molecular Weight Heparin Calcium on APTT and TT Levels in the Prevention of Venous Thrombosis after Cesarean Section in High-risk Pregnant Women
Objective To study the impacts of low molecular weight heparin calcium on activated partial thromboplastin time(APTT)and thrombin time(TT)in the prevention of venous thrombosis after cesarean section in high-risk pregnant women.Methods A total of 146 high-risk pregnant women of undergoing the cesarean section from January 2021 to January 2023 in our hospital were chosen as research subjects.According to random number table,women were assigned to control group(n=73,lower limb pneumatic pump)and observation group(n=73,lower limb pneumatic pump and low molecular weight heparin calcium).The coagulation function,platelet indices,lower extremity swelling,and risk of bleeding were compared between the two groups before and after treatment.Results There was no statistically significant difference in preoperative coagulation function and platelet count between the two groups(P＞0.05);after surgery,APTT,prothrombin time(PT)and TT values in the observation group were higher than control group;the fibrinogen(FIB)and platelet count were lower than control group,with statistically significant difference(P＜0.05).after surgery,gradeⅠ,Ⅱ lower extremity swelling rates in the observation group were lower than control group,with statistically significant difference(P＜0.05);the bleeding risks between observation group(one case)and control group(one case)were not significantly different(P＞0.05).Conclusion The preventive uses of low molecular weight heparin calcium in high-risk pregnant women after cesarean section can adjust the coagulation function indicators and effectively prevent the venous thrombosis,produce less impact on the bleeding risks,increase the treatment effects and safety.It is worthy of clinical application.
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