首页|短期胰岛素泵强化治疗脑卒中合并2型糖尿病患者的临床效果

短期胰岛素泵强化治疗脑卒中合并2型糖尿病患者的临床效果

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目的 探讨短期胰岛素泵强化治疗脑卒中合并 2 型糖尿病(T2DM)患者的临床效果.方法 选取许昌市人民医院在 2019 年 3 月至 2020 年 3 月期间收治的 70 例脑卒中合并T2DM患者作为研究对象,按照随机数字表法分为研究组(35例)和对照组(35例),对照组给予皮下注射胰岛素降糖治疗,研究组给予行胰岛素泵强化降糖治疗.治疗2周后,比较两组患者临床疗效、血糖控制情况、胰岛功能及运动功能.结果 研究组治疗有效率(94.29%)高于对照组(71.43%),差异有统计学意义(P<0.05).治疗后,两组空腹血糖(FPG)、餐后 2 h血糖(2hPG)水平低于治疗前,且研究组水平低于对照组,差异有统计学意义(P<0.05).治疗后,两组胰岛素曲线下面积(AUC)、胰岛β细胞功能指数(HOMA-β)高于治疗前,且研究组高于对照组,差异有统计学意义(P<0.05).治疗后,两组Fugl-Meyer运动功能评定量表(FMA)评分高于治疗前,且研究组评分高于对照组,差异有统计学意义(P<0.05).结论 脑卒中合并T2DM患者实施短期胰岛素泵强化治疗,可控制血糖水平,提高胰岛功能、运动功能.
Clinical Effect of Short-term Intensive Insulin Pump Treatment on Stroke Patients with Type 2 Diabetes Mellitus
Objective To explore the clinical effect of short-term intensive insulin pump treatment on stroke patients with type 2 diabetes mellitus(T2DM).Methods A total of 70 patients with stroke complicated with T2DM who were admitted in Xuchang People's Hospital from March 2019 to March 2020 were selected as the research objects,and they were randomly divided into the study group(35 cases)and the control group(35 cases)using a random number table method.The control group was given subcutaneous insulin injection to lower blood sugar,and the study group was given insulin pump to strengthen blood sugar lowering.After 2 weeks of treatment,the clinical efficacy,blood sugar control,pancreatic islet function and motor function were compared in the two groups.Results The effective rate of treatment in the study group(94.29%)was higher than that in the control group(71.43%),and the difference was statistically significant(P<0.05).After treatment,the levels of fasting blood glucose(FPG)and 2 h postprandial blood glucose(2hPG)in both groups were decreased(P<0.05),in comparision of the control group,the level of the study group was lower,and the difference was statistically significant(P<0.05).After treatment,the area under the insulin curve(AUC)and islet beta cell function index(HOMA-β)in both groups were increased,and in comparision of the control group,the study group was higher,and the difference was statistically significant(P<0.05).After treatment,Fugl-Meyer motor function assessment(FMA)scores in both groups were improved,and in comparision of the control group,the scores in the study group were higher,and the difference was statistically significant(P<0.05).Conclusion Intensive short-term insulin pump therapy for stroke patients with T2DM can control blood sugar levels,improve islet function and motor

type 2 diabetesstrokeintensive short-term insulin pump therapyblood sugar control

冀璐、李金燕

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许昌市人民医院 内分泌代谢科,河南 许昌 461000

2 型糖尿病 脑卒中 短期胰岛素泵强化治疗 血糖控制

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(2)
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