The Application Value of Xiyanping Injection Combined with Antibiotics in theTreatment of Elderly Emphysema with Pulmonary Infection
Objective To analyze the clinical effectiveness of Xiyanping injection with cefoperazone sodium and sulbactam sodium in elderly emphysema patients with pulmonary infections.Methods A total of 86 elderly patients with emphysema with pulmonary infection admitted to Pingyu County Central Hospital from January 2021 to August 2022 were selected as the study objects.There were 43 cases in each group according to random number table method.the control group was treated with cefoperazone sodium and sulbactam sodium;the observation group was treated with Xiyanping injection,cefoperazone sodium and sulbactam sodium.Group comparison results were observed through the clinical effects,sign and symptom disappearance time,hospital stays,forced expiratory volume in one second(FEV1),forced vital capacity(FVC),The ratio of forced expiratory volume in the first second to forced Vital capacity(FEV1/FVC),vital capacity(VC),white blood cell count(WBC),Interleukin-6(IL-6),Interleukin-8(IL-8),C-reactive protein(CRP)and adverse drug reactions.Results The clinical remission rates in the observation group(95.35%)were higher than control group(76.74%),the difference was statistically significant(P＜0.05);The disappearance time of cough,asthma,rales,wheezing,fever and hospitalization in the observation group were shorter than those in the control group,with statistical significance(P＜0.05).;After treatment,the levels of FEV1,FVC,FEV1/FVC and VC in both groups were increased,and the observation group was higher than the control group,the difference was statistically significant(P＜0.05).After treatment,the levels of WBC,IL-6,IL-8 and CRP in both groups were decreased,and the observation group was lower than the control group,the difference was statistically significant(P＜0.05).There was no significant difference in adverse reactions(diarrhea,nausea,palpitation and rash)between the two groups(P＞0.05).Conclusion Xiyangping injection plus cefoperazone sodium and sulbactam sodium have ideal curative effect on elderly patients with emphysema accompanied by lung infection,which can promote the disappearance of symptoms,improve lung function,reduce the secretion of inflammatory factors,shorten the length of hospital stay,and have high safety,which is worthy of use.
emphysemapulmonary infectionXiyanping injectioncefoperazone sodium and sulbactam sodium
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