The Therapeutic Effect of Xiao'er Feike Granule Combined with Azithromycin on Pediatric Pneumonia and its Influence on Inflammatory Factors Levels in Patients
Objective To analyze the impacts of Xiao'er Feike granule combined with Azithromycin in the treatment of pediatric pneumnoia and its impact on inflammatory factors levels.Methods A total of 72 children with pneumonia admitted to Nanyang Central Hospital from February 2022 to February 2023 were chosen as research subjects.According to random interval method,children were divided into control group(n=36,Azithromycin)and study group(n=36,Xiao'er Feike granule combined with Azithromycin).Compare the treatment effectiveness rate,the time for the disappearance of basic symptoms,changes in inflammatory factor indicators[C-reactive protein(CRP),procalcitonin(PCT),interleukin 6(IL-6),tumor necrosis factor alpha(TNF-α)],and changes in clinical pulmonary infection score(CPIS)score before and after treatment between the two groups.Results The treatment effectiveness rate of the study group(97.22%)was higher than that of the control group(80.56%),with a statistically significant difference(P＜0.05).The fever,cough,breath shortness and moist rale disappearance time in the study group were significantly shorter than control group,with a statistically significant difference(P＜0.05).Before treatment,there were no statistically significant difference in the levels of inflammatory factors between the two groups(P＞0.05);after treatment,the levels of CRP,PCT,TNF-α and IL-6 in both groups were significantly lower than before,and the levels in the study group were lower than those in the control group,with a statistically significant difference(P＜0.05).Before treatment,there was no statistically significant difference in CPIS scores between the two groups(P＞0.05).After treatment,the CPIS scores in both groups were significantly lower than before treatment,and the research group's score was lower than that of the control group,with a statistically significant difference(P＜0.05).Conclusion Xiao'er Feike granule combined with Azithromycin can effectively control the lung infections and inflammatory factors for pneumonia children.
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