Observation on the Effects of Specimen Hemolysis on the Levels of Electrolytes,myocardial Enzymes,Liver Function,and blood Lipids
Objective To investigate the effects of specimen hemolysis on electrolyte,myocardial enzymes,liver function,and blood lipid levels in biochemical tests.Methods A total of 78 physical examinees who underwent biochemical tests at Yuzhou Traditional Chinese Medicine Hospital from June 2022 to June 2023 were selected as the study subjects.All test samples were randomly divided into two parts,one of which was subjected to hemolysis treatment.The biochemical test indicators of the two samples were tested and compared.Results After hemolysis,the levels of potassium,chlorine,and calcium in the examinees increased compared to those before hemolysis,and the difference between the two was statistically significant(P<0.05),while the sodium level did not show significant changes before and after hemolysis,and the difference was not statistically significant(P>0.05).The levels of creatine kinase,creatine kinase isoenzyme,and N-terminal B-type natriuretic peptide precursor in the examinees after hemolysis were higher than those before hemolysis,and the differences were statistically significant(P<0.05).After hemolysis,the levels of alanine aminotransferase,aspartate aminotransferase,total bilirubin,and total protein in the examinees were higher than those before hemolysis,and the differences were statistically significant(P<0.05).The total cholesterol and triglyceride levels of the examinees after hemolysis were higher than those before hemolysis,and the differences were statistically significant(P<0.05).However,there was no significant difference in the levels of high-density lipoprotein cholesterol and low-density lipoprotein cholesterol between examinees before and after hemolysis,and the differences were not statistically significant(P>0.05).Conclusion Hemolysis of the specimen can cause changes in multiple indicators in the biochemical examination of the examinee,which will affect the results of the biochemical test and be disadvantageous to the subsequent diagnosis and treatment of the disease.In clinical testing,quality control of biochemical tests should be strengthened to avoid hemolysis in specimens as much as possible and improve the accuracy of biochemical test results.