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早期经口营养及经鼻空肠管营养应用于中重度急性胰腺炎的疗效对比

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目的 对比早期经口营养及经鼻空肠管营养应用于中重度急性胰腺炎的疗效。方法 选择郑州市第二人民医院 2020 年 5 月至 2023 年 5 月收治的中重度急性胰腺炎患者 90 例,按随机数字表法分成对照组和观察组,各 45 例。对照组予以经鼻空肠管营养治疗,观察组予以早期经口营养治疗,比较两组开始进食半流质食物时间、住院时间、住院费用、肠内营养相关并发症发生率、腹腔感染率、病死率、营养指标和感染指标。结果 两组开始进食半流质食物时间,住院时间,腹腔感染率,病死率,治疗 1 d、7 d、14 d前白蛋白、白细胞计数值,治疗 1 d、7 d白蛋白、C反应蛋白计数值比较,差异无统计学意义(P>0。05);观察组住院费用、肠内营养相关并发症发生率、治疗 14 d CRP值显著低于对照组,治疗 14 d白蛋白高于对照组,差异均有统计学意义(P<0。05)。结论 早期经口营养在中重度急性胰腺炎治疗中优于经鼻空肠管营养,可以降低患者肠内营养相关并发症发生率,改善肠内营养和感染指标,减少患者住院费用,提高患者生活质量,值得临床借鉴。
Comparison of the therapeutic Effects of early oral nutrition and nasal-jejunal nutrition in the Treatment of moderate to severe acute Pancreatitis
Objective To compare the therapeutic effects of early oral nutrition and nasal-jejunal nutrition on moderate to severe acute pancreatitis.Methods A total of 90 patients with moderate to severe acute pancreatitis admitted to the Second People's Hospital of Zhengzhou from May 2020 to May 2023 were divided into control group and observation group using a random number table method,with 45 cases in each group.The control group received nasal-jejunal nutrition treatment,while the observation group received early oral nutrition treatment.The start time of eating,hospitalization time,hospitalization costs,incidence of enteral nutrition related complications,abdominal infection rate,mortality rate,nutritional indicators,and infection indicators were compared between the two groups.Results There was no statistically significant difference(P>0.05)between the two groups in terms of starting eating time,hospitalization time,abdominal infection rate,mortality rate,albumin and white blood cell counts before treatment for 1,7,and 14 days,as well as albumin and C-reactive protein counts after treatment for 1 and 7 days;The hospitalization cost,incidence of enteral nutrition related complications,and CRP value after 14 days of treatment of the observation group were significantly lower than those of the control group,while albumin levels were higher than those of the control group after 14 days of treatment,with statistical significance(P<0.05).Conclusion Early oral nutrition is superior to nasal jejunal nutrition in the treatment of moderate to severe acute pancreatitis,which can reduce the incidence of complications related to enteral nutrition,improve enteral nutrition and infection indicators,reduce hospitalization costs,and improve patient quality of life.It is worth clinical reference.

acute pancreatitismoderate to severeearly oral nutritionnasal jejunal nutrition

姬旭慧、周燕、吕全军

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郑州市第二人民医院 临床营养科,河南 郑州 450006

郑州大学第一附属医院 临床营养科,河南 郑州 450000

急性胰腺炎 中重度 早期经口营养 经鼻空肠管营养

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(3)
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