Application of Dexmedetomidine Combined with Brachial Plexus Block Anesthesia in Elderly Patients with Upper Limb Fracture
Objective To explore the effect of dexmedetomidine(DEX)combined with brachial plexus block anesthesia in elderly patients with upper limb fracture.Methods A total of 106 elderly patients with upper limb fracture who were treated in the Third People's Hospital of Zhengzhou City from June 2021 to May 2022 were selected,by random number table method,they were divided into the study group and the control group,with 53 cases in each group.Midazolam combined with brachial plexus block was given in the control group.DEX combined with brachial plexus block was given in the study group.The sedation score,nerve block effect,hemodynamic indexes and adverse reactions at admission(T0),10 minutes of surgery(T1),the time of skin incision(T2),30 minutes of surgery(T3),the end of surgery(T4)were compared o the two groups.Results The Ramsay sedation scores of T2,T3 and T4 in both groups were lower than those of T1(P<0.05),but in comparision of the control group,the Ramsay sedation scores of T2,T3 and T4 in the study group were higher,the difference was statistically significant(P<0.05).There was no significant difference in the onset time of sensory block and motor block between the two groups(P>0.05).In comparision of the control group,the duration of sensory block and motor block in the study group was longer,the difference was statistically significant(P<0.05).The heart rate and blood pressure at T1,T2,T3,T4 in both groups were lower than T0 but in comparision of the control group,the study group at T3 and T4 were higher,the difference was statistically significant(P<0.05).In comparision of the control group(18.87%),the incidence of adverse reactions in the study group(3.77%)was lower,the difference was statistically significant(P<0.05).Conclusion DEX combined with brachial plexus block anesthesia can improve the sedative effect,which have good nerve block effect,reduce the occurrence of adverse reactions,and have little impact on hemodynamic indexes in elderly patients with upper limb fracture surgery.