The Improvement Effect of non-invasive Ventilation combined with Rehabilitation Training on Lung Function in Patients with chronic obstructive pulmonary disease and respiratory Failure
Objective To explore the improvement effect of non-invasive ventilation combined with rehabilitation training on lung function in patients with chronic obstructive pulmonary disease(COPD)and respiratory failure.Methods A total of 98 COPD patients complicated with respiratory failure admitted to Luohe Maternal and Child Health Hospital from January 2020 to December 2022 were randomly divided into control group and observation group,with 49 cases in each group.The control group received non-invasive ventilation treatment,while the observation group received rehabilitation training on this basis.The clinical indexes,pulmonary function indexes,cardiopulmonary oxygenation and the incidence of complications were compared between the two groups.Results The improvement of various clinical indicators in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no statistically significant difference in lung function levels[forced expiratory volume in 1 second(FEV1),forced vital capacity(FVC),maximal voluntary ventilation(MVV)]between the two groups(P＞0.05);After treatment,the levels of FEV1,FVC,and MVV in the observation group were significantly higher than those in the control group,with statistical significance(P＜0.05).Before treatment,there was no statistically significant difference in arterial blood gas indicators between the two groups(P＞0.05);After treatment,the observation group had lower levels of partial pressure of carbon dioxide(PaCO2)compared to the control group,and higher levels of partial pressure of oxygen(PaO2)and oxygen saturation(SaO2)compared to the control group,with statistically significant differences(P＜0.05).After treatment,the cardiorespiratory oxygenation ability of both groups was improved,and the maximum oxygen uptake(VO2max),metabolic equivalent(MET),and rating of perceived exertion(RPE)levels in the observation group were higher than those in the control group,with statistical significance(P＜0.05).The incidence of complications in the observation group(6.12%)was lower than that in the control group(24.49%),and the difference was statistically significant(P＜0.05).Conclusion Non-invasive ventilation combined with rehabilitation training can effectively improve lung function and arterial blood gas indicators in patients with chronic obstructive pulmonary disease and respiratory failure,enhance cardiopulmonary oxygenation ability,reduce the incidence of complications,and shorten the duration of the disease.
chronic obstructive pulmonary diseaserespiratory failurenon-invasive ventilationrehabilitation trainingpulmonary function
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