首页|宫腔镜下宫腔粘连分离术后粘连复发影响因素分析

宫腔镜下宫腔粘连分离术后粘连复发影响因素分析

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目的 探讨宫腔镜下宫腔粘连分离术后粘连复发的影响因素,并利用分析结果构建数学模型,分析数学模型的预测效能。方法 将 2015 年 1 月至 2022 年 12 月在睢县妇幼保健院接受宫腔镜下宫腔粘连分离手术的 327 名患者的数据资料实施回顾性分析。分析全部患者术后1年内的粘连复发情况。宫腔镜下宫腔粘连分离术后粘连复发的单因素、多因素分析。宫腔镜下宫腔粘连分离术后粘连复发的预测模型构建和预测效能分析。结果 纳入研究的患者之中,共有47人在术后1年内发生粘连复发,复发率为14。37%。logistic多因素分析结果显示,人工流产次数、宫腔内的手术次数、清宫术后闭经情况、宫腔粘连性质、宫腔粘连范围、术后放置物理屏障的情况、术后雌激素使用剂量是宫腔镜下宫腔粘连分离术后粘连复发的独立危险因素,差异具有统计学意义(P<0。05)。依据多因素分析所筛选出来的变量构建列线图风险模型一致性指数(C-index)为 0。713。校准曲线平均绝对误差为 0。013。利用回归模型的独立危险因素以及风险回归模型对宫腔镜下宫腔粘连分离术后粘连复发的列线图进行受试者工作特征(ROC)曲线的预测,约登指数分别为45。23%、48。02%、30。40%、36。70%、44。16%、34。95%、32。65%、78。65%。结论 宫腔镜下宫腔粘连分离手术后出现粘连复发同人工流产次数增多等因素有关;基于各影响因素构建的风险回归模型能够较为良好的预测患者粘连复发风险,并指导给予针对性的干预。
Analysis of the Factors influencing the Recurrence of intrauterine Adhesions after hysteroscopic Adhesions-separation
Objective To explore the influencing factors of adhesion recurrence after hysteroscopic separation of intrauterine adhesions,and to construct a mathematical model based on the analysis results to analyze the predictive performance of the mathematical model.Methods A retrospective analysis was conducted on the data of 327 patients who underwent hysteroscopic separation surgery for intrauterine adhesions in our hospital from January 2015 to December 2022.The recurrence of adhesions in all patients within one year after surgery were analyzed.Univariate and multivariate analysis of adhesion recurrence after hysteroscopic separation of intrauterine adhesions.Construction and predictive performance analysis of a predictive model for postoperative adhesion recurrence after hysteroscopic separation of intrauterine adhesions.Results Among the patients included in the study,a total of 47 experienced adhesion recurrence within 1 year after surgery,with a recurrence rate of 14.37%.The results of logistic multivariate analysis showed that the number of induced abortions,number of intrauterine surgeries,amenorrhea after curettage,nature of intrauterine adhesions,range of intrauterine adhesions,placement of physical barriers after surgery,and dosage of estrogen used after surgery were independent risk factors for postoperative adhesion recurrence after hysteroscopic separation of intrauterine adhesions,and the differences were statistically significant(P<0.05).The consistency index(C-index)of the column chart risk model constructed based on the selected variables from multiple factor analysis is 0.713.The average absolute error of the calibration curve is 0.013.The independent risk factors of regression models and the risk regression model were used to predict the receiver operating characteristic(ROC)curve of postoperative adhesion recurrence after hysteroscopic separation of intrauterine adhesions.The Jordan indices were 45.23%,48.02%,30.40%,36.70%,44.16%,34.95%,32.65%,and 78.65%,respectively.Conclusion The recurrence of intrauterine adhesions after hysteroscopic separation surgery is related to factors such as an increase in the number of induced abortions;The risk regression model constructed based on various influencing factors can effectively predict the risk of adhesion recurrence in patients and guide targeted interventions.

hysteroscopyseparation of intrauterine adhesionsrecurrenceartificial abortionestrogen

陈雪梅

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睢县妇幼保健院 妇科,河南 商丘 476900

宫腔镜 宫腔粘连分离 复发 人工流产 雌激素

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(4)
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