Analysis of the Factors influencing the Recurrence of intrauterine Adhesions after hysteroscopic Adhesions-separation
Objective To explore the influencing factors of adhesion recurrence after hysteroscopic separation of intrauterine adhesions,and to construct a mathematical model based on the analysis results to analyze the predictive performance of the mathematical model.Methods A retrospective analysis was conducted on the data of 327 patients who underwent hysteroscopic separation surgery for intrauterine adhesions in our hospital from January 2015 to December 2022.The recurrence of adhesions in all patients within one year after surgery were analyzed.Univariate and multivariate analysis of adhesion recurrence after hysteroscopic separation of intrauterine adhesions.Construction and predictive performance analysis of a predictive model for postoperative adhesion recurrence after hysteroscopic separation of intrauterine adhesions.Results Among the patients included in the study,a total of 47 experienced adhesion recurrence within 1 year after surgery,with a recurrence rate of 14.37%.The results of logistic multivariate analysis showed that the number of induced abortions,number of intrauterine surgeries,amenorrhea after curettage,nature of intrauterine adhesions,range of intrauterine adhesions,placement of physical barriers after surgery,and dosage of estrogen used after surgery were independent risk factors for postoperative adhesion recurrence after hysteroscopic separation of intrauterine adhesions,and the differences were statistically significant(P<0.05).The consistency index(C-index)of the column chart risk model constructed based on the selected variables from multiple factor analysis is 0.713.The average absolute error of the calibration curve is 0.013.The independent risk factors of regression models and the risk regression model were used to predict the receiver operating characteristic(ROC)curve of postoperative adhesion recurrence after hysteroscopic separation of intrauterine adhesions.The Jordan indices were 45.23%,48.02%,30.40%,36.70%,44.16%,34.95%,32.65%,and 78.65%,respectively.Conclusion The recurrence of intrauterine adhesions after hysteroscopic separation surgery is related to factors such as an increase in the number of induced abortions;The risk regression model constructed based on various influencing factors can effectively predict the risk of adhesion recurrence in patients and guide targeted interventions.
hysteroscopyseparation of intrauterine adhesionsrecurrenceartificial abortionestrogen