首页|术前不同剂量罗哌卡因腹横肌平面阻滞对腹腔镜卵巢癌根治术患者的影响差异分析

术前不同剂量罗哌卡因腹横肌平面阻滞对腹腔镜卵巢癌根治术患者的影响差异分析

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目的 分析术前不同剂量罗哌卡因腹横肌平面阻滞对腹腔镜卵巢癌根治术患者的影响差异。方法 选择 2020年 1 月至 2023 年 12 月之间在商丘仁和中医院接受腹腔镜下卵巢癌根治手术的女性患者 102 人作为研究对象。依据随机数字表法对入组患者实施分组。分为对照组(n=51)以及观察组(n=51)。对照组患者使用低剂量的罗哌卡因注射液完成腹横肌平面阻滞,药物的总使用剂量为 0。3 mL/kg,观察组患者使用高剂量的罗哌卡因注射液完成阻滞,药物的总使用剂量为 0。5 mL/kg。记录两组患者的手术后麻醉苏醒质量相关指标、患者在手术前、手术后 24 h的认知能力、患者在术后不同时间点静息状态下的疼痛程度以及两组患者在术后 24 h内的舒芬太尼使用剂量以及镇痛泵有效按压次数。结果 两组患者手术后的拔管时间、拔管时的呼吸频率的数据比较,差异无统计学意义(P>0。05)。观察组的咳嗽评分低于对照组,观察组的Ramsay镇静评分高于对照组,差异具有统计学意义(P<0。05)。两组患者手术前以及手术后24 h的简易智能状态检查量表(MMSE)和蒙特利尔认知评估量表(MoCA)相比,差异无统计学意义(P>0。05)。两组患者手术后 24 h的MMSE评分、MoCA评分均低于本组手术前,差异具有统计学意义(P<0。05)。重复测量方差分析显示,对照组静息状态下的视觉模拟评分(VAS)高于观察组,差异具有统计学意义(F=36。231,P<0。05);术后不同时间点静息状态下的VAS评分相比,差异有统计学意义(F=28。654,P<0。05),且两两对比中,任意两个时间点的VAS评分数据差异均有统计学意义(P<0。05);在手术后不同时间点静息状态下VAS评分具有交互作用(F=17。087,P<0。05)。观察组患者在术后 24 h内的舒芬太尼使用剂量以及镇痛泵有效按压次数均低于对照组,差异具有统计学意义(P<0。05)。结论 使用 0。5 mL/kg的罗哌卡因实施腹腔镜下卵巢癌根治手术前的腹横肌平面神经阻滞,能够有效的改善术后患者的疼痛严重程度,且不会对患者的认知功能造成明显损伤,同时可以提升患者的苏醒质量,改善镇痛效果。
Analysis of the Different Effects of Preoperative Different Doses of Ropivacaine Transversus Abdominis Plane Block on Patients Undergoing Laparoscopic Radical Ovarian Cancer Surgery
Objective To analyze the different effects of preoperative different doses of ropivacaine transversus abdominis plane block on patients undergoing laparoscopic radical ovarian cancer surgery.Methods 102 female patients who underwent laparoscopic radical ovarian cancer surgery in Shangqiu Renhe Traditional Chinese Medicine Hospital from January 2020 to December 2023 were selected as the research subjects.The enrolled patients were divided into groups according to the random number table method.They were divided into the control group(n=51)and the observation group(n=51).The control group patients used a low dose of ropivacaine injection to complete the transversus abdominis plane block,and the total dose of the drug was 0.3 mL/kg.The observation group patients used a high dose of ropivacaine injection to complete the block,and the total dose of the drug was 0.5 mL/kg.Record the postoperative anesthesia recovery quality-related indicators of the two groups of patients,the cognitive ability of the patients before and 24 hours after the surgery,the pain level of the patients at different time points after the surgery at rest,and the use of sufentanil within 24 hours after the surgery and the effective pressure of the analgesic pump Times.Results There was no statistical significance in the comparison of the data of the extubation time and the respiratory rate at the time of extubation after the operation of the two groups of patients(P>0.05).The cough score of the observation group was lower than that of the control group,and the Ramsay sedation score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no statistical significance in the comparison of the Mini-Mental State Examination(MMSE)and Montreal Cognitive Assessment(MoCA)before and 24 hours after the operation of the two groups of patients(P>0.05).The MMSE score and MoCA score of the two groups of patients 24 hours after the operation were lower than those before the operation of the group,and the difference was statistically significant(P<0.05).Repeated measures analysis of variance showed that the visual analog score(VAS)of the control group at rest was higher than that of the observation group,and the difference was statistically significant(F=36.231,P<0.05);the VAS score at different time points after the operation at rest was compared,and the difference was statistically significant(F=28.654,P<0.05),and in the pairwise comparison,the difference in VAS score data at any two time points was statistically significant(P<0.05);the VAS score at different time points after the operation at rest had an interaction(F=17.087,P<0.05).The use of sufentanil within 24 hours after the operation and the effective pressure times of the analgesic pump in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of 0.5 mL/kg of ropivacaine to perform transversus abdominis plane nerve block before laparoscopic radical ovarian cancer surgery can effectively improve the severity of postoperative pain in patients,and will not cause obvious damage to the cognitive function of patients,and can also improve the recovery quality of patients.,Improve the analgesic effect.

ropivacainetransversus abdominislaparoscopyovarian cancersufentanil

张鹏

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商丘仁和中医院 麻醉科,河南 商丘 476000

罗哌卡因 腹横肌 腹腔镜 卵巢癌 舒芬太尼

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(4)
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