Clinical Efficacy of ultrasound-guided percutaneous transhepatic Gallbladder Puncture Drainage for the Treatment of acute Cholecystitis
Objective To explore the clinical effect of ultrasound-guided percutaneous transhepatic gallbladder drainage(PTGBD)in the treatment of acute cholecystitis(AC)patients.Methods A total of 100 AC patients who received treatment at the First People's Hospital of Xinxiang City from September 2021 to October 2023 were selected.They were randomly divided into study group(n=50)and control group(n=50)using a random number table method.The control group received laparoscopic cholecystectomy(LC)treatment,while the study group received ultrasound-guided PTGBD treatment.Perioperative indicators,pain level[Visual Analog Scale(VAS)],liver function indicators[serum alkaline phosphatase(ALP),indirect bilirubin(IBIL),total bilirubin(TBIL)],and inflammatory stress indicators[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),C-reactive protein(CRP),white blood cell count(WBC)]and postoperative complications were measured in both groups.Results The study group had shorter surgical time,first anal exhaust time,hospitalization time,and less intraoperative bleeding compared to those in the control group,with statistically significant differences(P＜0.05);The postoperative VAS scores of the two groups decreased compared to before surgery,and the postoperative VAS scores of the study group were lower than those of the control group,with a statistically significant difference(P＜0.05);The levels of postoperative ALP,IBIL,and TBIL in the two groups decreased compared to before surgery,and the levels of the above indicators in the study group were lower than those in the control group after surgery,with statistical significance(P＜0.05);The levels of ALP,IBIL and TBIL in the two groups decreased after operation,and the levels of these indexes in the study group were lower than those in the control group,the difference was statistically significant(P＜0.05);The levels of TNF-α,IL-6,CRP and WBC in the two groups after operation were lower than those before operation,and the levels in the study group were lower than those in the control group(P＜0.05);The incidence of postoperative complications in the study group(4.00%)was significantly lower than that in the control group(18.00%)(P＜0.05).Conclusion The application of ultrasound-guided PTGBD in the treatment of AC patients can improve perioperative indicators,reduce pain levels,improve liver function indicators and inflammatory stress indicators,and reduce postoperative complications.
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NSTL
万方数据
维普
