The Comparative Studies of Two Transfusion Treatment Strategies for Severe Burn Patients During Non-Shock Phase
Objective To analyze the clinical effects of two transfusion treatment regimens on patients with severe burns(non-shock phase).Methods A retrospective analysis was conducted on 88 severe burn patients admitted to Zhengzhou First People's Hospital from April 2020 to April 2023.According to the different transfusion therapies,patients were assigned to group A(restrictive transfusion)and group B(liberal transfusion).44 cases each,Intergroup comparisons were made regarding blood transfusion volume,transfusion effectiveness[calculate the amount of change per unit of red blood cells before and after transfusion,,Δ Red blood cells(RBC)Δ Hemoglobin(Hb)and Δ Hematocrit(HCT)],electrolyte changes,coagulation function,and the risk of adverse reactions.Results The input RBC(red blood cell),plasma and total blood volume in group A were lower than group B,with statistically significant difference(P＜0.05);Effectiveness of Group A Blood Transfusion Δ RBC Δ The Hb index was higher than that of Group B,with statistically significant difference(P＜0.05);after therapy,the sodium ion(Na+)and calcium ion(Ca2+)indicators in Group A were higher than those in Group B,and the potassium ion(K+)indicators were lower than those in Group B,with statistical significance(P＜0.05);after therapy,the prothrombin time(PT),thrombin time(TT),and activated partial thromboplastin time(APTT)in group A were higher than those in group B,while the fibrinogen concentration(FIB)was lower than that in group B,with statistical significance(P＜0.05);the adverse event rates in group A(9.09%)and group B(20.45%)were not significantly different(P＞0.05).Conclusion In the non-shock phase,both of the restrictive transfusion and liberal transfusion have the fair treatment effects for severe burn patients;However,restrictive transfusion treatment can reduce the frequency of blood transfusion,thereby reducing the potential risks of blood transfusion and saving blood resources.This is of great significance for the rational and safe use of blood in clinical practice.
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维普
