Observation of Low-dose Administration of Furosemide and Dopamine in Regulating Patients with Heart Failure and Renal Insufficiency
Objective To analyze the effect of combined treatment with furosemide and low-dose dopamine in patients with heart failure(CHF)and renal insufficiency.Methods A total of 98 patients with CHF complicated with renal insufficiency admitted to the First People's Hospital of Shangqiu City between October 2022 and October 2023 were selected as study cases,and were divided into a control group treated with furosemide(n=49)and a study group(n=49)treated with low-dose dopamine based on the control group using odd even grouping method.A comparison was made between the two groups in terms of heart and kidney function,quality of life score,and adverse reactions.Results After treatment,both groups showed an increase in left ventricular ejection fraction(LVEF)and 6-minute walking distance(6MWT),while a decrease in brain natriuretic peptide(BNP),the LVEF and 6MWT indicators in the study group were higher than those in the control group,while the BNP indicators was lower than those in the control group,and the difference was statistically significant(P＜0.01);After treatment,the indicators of blood creatinine(Scr),blood urea nitrogen(BUN),and blood uric acid(UA)in both groups decreased,and the indicators in the study group were lower than those in the control group,with statistical significance(P＜0.01);After treatment,the CQQC scores of both groups increased,and the study group was higher than the control group,with a statistically significant difference(P＜0.05).The incidence of adverse reactions in the study group(6.12%)was lower than that in the control group(20.14%)(P＜0.05).Conclusion The combination of furosemide and low-dose dopamine treatment for patients with CHF and renal insufficiency can effectively improve their cardiovascular and renal function,exert the effect of improving quality of life,and demonstrate good safety.
furosemidedopaminelow dose administrationheart failure with renal insufficiencycardiorenal functionquality of life
国家科技期刊平台
NSTL
万方数据
维普
