Observation on the Therapeutic Effect of Amlodipine Atorvastatin Calcium Tablets on Patients with Hypertension and Coronary Heart Disease
Objective To explore the actual therapeutic effect of the compound preparation"Amlodipine Atorvastatin Calcium Tablets"on patients with hypertension and coronary heart disease.Methods A total of 86 patients with hypertension complicated with coronary heart disease from May 2021 to December 2022 were included as the study subjects.They were randomly divided into a control group and a study group(odd numbered individuals were included in the control group,and even numbered individuals were included in the study group)using a random number table method,with 43 cases in each group.The control group was only treated with amlodipine;The research group used amlodipine atorvastatin calcium tablets for treatment.Compare the total effective rate of treatment,relevant indicators of efficacy before and after treatment[blood pressure level,cardiac function indicators,Minnesota Living with Heart Failure Questionnaire(MLHFQ)],and adverse reactions.Results The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the blood pressure in the study group was lower than that in the control group,and the difference was statistically significant(P＜0.05);After treatment,the study group had higher cardiac output,left ventricular ejection fraction,and stroke output than the control group,while the left ventricular end systolic and end diastolic diameter was lower than the control group,with statistically significant differences(P＜0.05);After treatment,the MLHFQ score of the study group was lower than that of the control group(P＜0.05);There was no significant difference in the incidence of adverse reactions during medication between the control group and the study group(P＞0.05).Conclusion The use of a composite formulation of amlodipine atorvastatin calcium tablets for the treatment of hypertension and coronary heart disease has a definite therapeutic effect,and can simultaneously improve heart function and control blood pressure,making it worthy of application.
国家科技期刊平台
NSTL
万方数据
维普
