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部分二类精神药品使用现况调查分析

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目的 分析第二类精神药品(简称"精二药品")使用现况。方法 回顾性选取河南省直属机关第一门诊部2022 年 1 月至 2022 年 12 月期间 8 000 张精二药品处方,均为口服药剂处方,分析精二药品使用现况。结果 2022 年 1月至 2022 年 12 月期间本院开出 8 000 张精二药品处方中,其中艾司唑仑占比 35。15%,阿普唑仑占比 25。24%,右佐匹克隆占比 14。58%,酒石酸唑吡坦片占比 13。35%,氯硝西泮占比 11。69%。结合总用药量可知,艾司唑仑>阿普唑仑>酒石酸唑吡坦片>氯硝西泮>右佐匹克隆;结合用药频度(DDDs)可知,艾司唑仑>阿普唑仑>氯硝西泮>右佐匹克隆>酒石酸唑吡坦片;结合药物利用指数(DUI)可知,艾司唑仑、阿普唑仑、酒石酸唑吡坦片、右佐匹克隆、氯硝西泮用药基本合理。按照B/A 值可知,艾司唑仑与阿普唑仑价格与患者的接受程度的同步性高,氯硝西泮、右佐匹克隆价格便宜/使用频率高,酒石酸唑吡坦片药品价格较高或患者的接受度较低。>18~59岁人群应用精二药品的占比较多,其次为>59 岁人群。结论 中青年人群应用精二药品口服剂的人数最多,其次为老年人群,且艾司唑仑和阿普唑仑用量最大,其次为右佐匹克隆、酒石酸唑吡坦片,最后为氯硝西泮。
Analysis of the Current Usage of Certain Class Ⅱ Psychotropic Drugs
Objective To analyze the current usage status of Class Ⅱ psychotropic drugs(referred to as"Jing Er drugs").Methods A retrospective selection was conducted on 8000 prescriptions of Jing Er drugs from the First Outpatient Department of Henan Province's directly affiliated institutions from January 2022 to December 2022,all of which were oral medication prescriptions.The current use of Jing Er drugs was analyzed.Results During the period from January 2022 to December 2022,our hospital issued 8000 prescriptions for essential medicines,of which esomeprazole accounted for 35.15%,alprazolam accounted for 25.24%,dexzopiclone accounted for 14.58%,zolpidem tartrate tablets accounted for 13.35%,and clonazepam accounted for 11.69%.Based on the total dosage,it can be concluded that esomezolam>alprazolam>zolpidem tartrate tablets>clonazepam>dexzopiclone;Combining Defined Daily Doses(DDDs),it can be concluded that esomeprazole>alprazolam>clonazepam>dexzopiclone>zolpidem tartrate tablets;Based on the Drug Utilization Index(DUI),it can be concluded that the use of esomeprazole,alprazolam,zolpidem tartrate tablets,dexzopiclone,and clonazepam is generally reasonable.According to the B/A value,it can be seen that the synchronization between the prices of esomeprazole and alprazolam and the patient's acceptance is high,while the prices of clonazepam and dexzopiclone are cheap/frequently used,and the prices of zolpidem tartrate tablets are high or the patient's acceptance is low The proportion of people aged 18-59 who use Jing Er drugs is relatively high,followed by those aged over 59.Conclusion The majority of middle-aged and young people use Jing'er drug oral supplements,followed by the elderly population,and the highest doses of esomeprazole and alprazolam,followed by dexzopiclone,zolpidem tartrate tablets,and finally clonazepam.

psychotropic drugsthe second categorydosage of medicationreasonable situation

李丹、李晓丽

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河南省直属机关第一门诊部 药剂科,河南 郑州 450000

安阳地区医院 药学部,河南 安阳 455000

精神药品 第二类 用药量 合理状况

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(5)
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