首页|益气维血胶囊联合右旋糖酐铁治疗妊娠期缺铁性贫血的临床效果

益气维血胶囊联合右旋糖酐铁治疗妊娠期缺铁性贫血的临床效果

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目的 探讨妊娠期缺铁性贫血(IDA)患者采用益气维血胶囊联合右旋糖酐铁治疗的临床效果。方法 选取 2018 年 1 月至 2023 年 9 月在本院接受治疗的 100 例妊娠期IDA患者,以随机数字表法分为研究组(n=50)与对照组(n=50),对照组采用右旋糖酐铁治疗,研究组采用益气维血胶囊联合右旋糖酐铁治疗,对两组临床疗效、血常规指标、铁代谢指标、不良妊娠结局及不良反应进行比较。结果 研究组治疗有效率(96。00%)高于对照组(82。00%),差异有统计学意义(P<0。05);两组治疗后血常规指标[平均红细胞体积(MCV)、血红蛋白(Hb)、红细胞计数(RBC)]升高,差异有统计学意义(P<0。05),研究组较对照组更高,差异有统计学意义(P<0。05);两组治疗后血清铁蛋白(SF)、血清铁(SI)升高,差异有统计学意义(P<0。05),可溶性转铁蛋白受体(STFR)下降,差异有统计学意义(P<0。05),研究组SF、SI较对照组更高,差异有统计学意义(P<0。05),STFR更低,差异有统计学意义(P<0。05);研究组不良妊娠结局发生率(2。00%)低于对照组(16。00%),差异有统计学意义(P<0。05);研究组不良反应发生率(6。00%)低于对照组(24。00%),差异有统计学意义(P<0。05)。结论 益气维血胶囊联合右旋糖酐铁应用于妊娠期IDA患者的治疗中,能够提高临床疗效,改善血常规、铁代谢指标,降低不良妊娠结局、不良反应发生率。
Clinical Efficacy of Yiqi Weixue Capsules Combined with Ferric Glycinate Chelate in the Treatment of Iron Deficiency Anemia during Pregnancy
Objective To investigate the clinical efficacy of Yiqi Weixue capsules combined with ferric glycinate chelate in the treatment of iron deficiency anemia(IDA)during pregnancy.Methods A total of 100 pregnant women with IDA treated in our hospital from January 2018 to September 2023 were selected and randomly divided into a study group(n=50)and a control group(n=50)using a random number table.The control group was treated with ferric glycinate chelate,while the study group was treated with Yiqi Weixue capsules combined with ferric glycinate chelate.The clinical efficacy,blood routine indicators,iron metabolism indicators,adverse pregnancy outcomes,and adverse reactions were compared between the two groups.Results The effective rate of treatment in the study group(96.00%)was higher than that in the control group(82.00%),with a statistically significant difference(P<0.05);the blood routine indicators[mean corpuscular volume(MCV),hemoglobin(Hb),red blood cell count(RBC)]increased in both groups after treatment,with statistically significant differences(P<0.05),and the study group was higher than the control group,with statistically significant differences(P<0.05);the serum ferritin(SF)and serum iron(SI)levels increased after treatment in both groups,with statistically significant differences(P<0.05),and the soluble transferrin receptor(STFR)decreased,with statistically significant differences(P<0.05),the SF and SI levels in the study group were higher than those in the control group,with statistically significant differences(P<0.05),and the STFR level was lower,with statistically significant differences(P<0.05);the incidence of adverse pregnancy outcomes in the study group(2.00%)was lower than that in the control group(16.00%),with a statistically significant difference(P<0.05);the incidence of adverse reactions in the study group(6.00%)was lower than that in the control group(24.00%),with a statistically significant difference(P<0.05).Conclusion The application of Yiqi Weixue capsules combined with ferric glycinate chelate in the treatment of IDA during pregnancy can improve clinical efficacy,normalize blood routine and iron metabolism indicators,and reduce the incidence of adverse pregnancy outcomes and adverse reactions.

Yiqi Weixue capsulesferric glycinate chelateiron deficiency anemia during pregnancy

张晓艳

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舞阳县妇幼保健院 妇产科,河南 漯河 462400

益气维血胶囊 右旋糖酐铁 妊娠期缺铁性贫血

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(5)
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