首页|血清肌酐、尿素氮与胱抑素C水平检测与肾病综合征病情严重程度的关系研究

血清肌酐、尿素氮与胱抑素C水平检测与肾病综合征病情严重程度的关系研究

扫码查看
目的 探讨血清肌酐(Scr)、尿素氮(BUN)和胱抑素C(CysC)水平检测与肾病综合征(NS)病情严重程度的关系。方法 选取南阳市第二人民医院 2021 年 8 月至 2023 年 10 月收治的 168 例NS患者作为本次研究组研究对象,根据病情严重程度将研究组分为轻度肾功能损伤组(80 例)与重度肾功能损伤组(88 例),同时纳入本院同期体检的健康者作为参照组,共计 80 例,均对其开展Scr、BUN、CysC检测,分析三种指标在对健康者及NS不同严重程度中的区别。结果 研究组Scr、BUN与CysC水平均高于参照组,差异有统计学意义(P<0。05);重度肾功能损伤组Scr、BUN与CysC水平均高于轻度肾功能损伤组,差异有统计学意义(P<0。05)。结论 Scr、BUN与CysC三种指标用于检测NS能够有效帮助临床医师辨别NS病情严重程度,为后期治疗工作的开展提供科学参考,临床价值较高。
Study on the Relationship between Serum Creatinine,Urea Nitrogen,and Cystatin C Levels and the Severity of nephrotic Syndrome
Objective To explore the relationship between serum creatinine(Scr),blood urea nitrogen(BUN),and cystatin C(CysC)levels and the severity of nephrotic syndrome(NS).Methods A total of 168 patients with NS admitted to the Second People's Hospital of Nanyang City from August 2021 to October 2023 were selected as the research subjects for this study group.The study group was divided into mild renal function injury group(80 cases)and severe renal function injury group(88 cases)based on the severity of the disease.A total of 80 healthy individuals who underwent physical examinations at the same time were included as the control group.Scr,BUN,and CysC tests were conducted on them,and the differences of the three indicators in different severity levels of healthy individuals and NS were analyzed.Results The levels of Scr,BUN,and CysC in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05);The levels of Scr,BUN,and CysC in the severe renal function injury group were higher than those in the mild renal function injury group,and the differences were statistically significant(P<0.05).Conclusion The use of Scr,BUN,and CysC as three indicators to detect NS can effectively help clinical physicians distinguish the severity of NS and provide scientific reference for later treatment work,with high clinical value.

nephrotic syndromeserum creatinineurea nitrogencystatin Crenal dysfunction

王东、李娟、王艳

展开 >

南阳市第二人民医院 检验科,河南 南阳 473000

南阳市第二人民医院 泌尿外科,河南 南阳 473000

肾病综合征 血清肌酐 尿素氮 胱抑素C 肾功能受损

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(5)
  • 18