Study on the Relationship between Serum Creatinine,Urea Nitrogen,and Cystatin C Levels and the Severity of nephrotic Syndrome
Objective To explore the relationship between serum creatinine(Scr),blood urea nitrogen(BUN),and cystatin C(CysC)levels and the severity of nephrotic syndrome(NS).Methods A total of 168 patients with NS admitted to the Second People's Hospital of Nanyang City from August 2021 to October 2023 were selected as the research subjects for this study group.The study group was divided into mild renal function injury group(80 cases)and severe renal function injury group(88 cases)based on the severity of the disease.A total of 80 healthy individuals who underwent physical examinations at the same time were included as the control group.Scr,BUN,and CysC tests were conducted on them,and the differences of the three indicators in different severity levels of healthy individuals and NS were analyzed.Results The levels of Scr,BUN,and CysC in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05);The levels of Scr,BUN,and CysC in the severe renal function injury group were higher than those in the mild renal function injury group,and the differences were statistically significant(P<0.05).Conclusion The use of Scr,BUN,and CysC as three indicators to detect NS can effectively help clinical physicians distinguish the severity of NS and provide scientific reference for later treatment work,with high clinical value.