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乙肝疫苗接种预防和控制乙肝感染的价值

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目的 对预防与控制乙肝感染的乙肝疫苗接种效果及其价值分析。方法 筛选 2022 年 1 月-12 月 120 例接种乙肝疫苗儿童作为研究对象,依年龄分组,即A(<2 岁)、B(2~6 岁)、C(7~10 岁)三组,针对不同年龄段乙肝疫苗接种后免疫应答情况统计对比,并比较不同年龄段抗体水平。结果 患儿免疫应答有效率经对比,A、B、C组分别是85。37%、69。23%、60。00%,差异有统计学意义(P<0。05);三组儿童抗体水平接种前对比差异无统计学意义(P>0。05),接种后A组抗体水平高于接种前,并高于B、C组,差异有统计学意义(P<0。05),B、C组抗体水平与接种前对比差异无统计学意义(P>0。05)。结论 乙肝疫苗能积极预防与控制乙肝感染率,儿童接种年龄越小免疫应答率越高,应尽早接种乙肝疫苗。
Clinical Value of Hepatitis B Vaccination on the Prevention and Control of Hepatitis B Virus Infections
Objective To analyze the vaccination effect and value of hepatitis B vaccine to prevent and control hepatitis B infection.Methods A total of 120 children vaccinated with hepatitis B vaccine from January to December 2022 were selected as the research objects.They were divided into three groups according to age,namely,A(<2 years old),B(2-6 years old),and C(7-10 years old).The immune responses after hepatitis B vaccination in different age groups were statistically compared,and the antibody levels in different age groups were compared.Results The effective rates of immune response in the children were compared,groups A,B,and C were 85.37%,69.23%,and 60.00%,respectively,and the difference was statistically significant(P<0.05).Before vaccination,there was no difference in the antibody levels among the three groups of children(P>0.05).After vaccination,the antibody levels in Group A were higher than before vaccination,and higher than Group B and C,and the difference was statistically significant(P<0.05).There was no statistically significant difference between Groups B and C and before vaccination(P>0.05).Conclusion Hepatitis B vaccine can actively prevent and control the infection rate of hepatitis B.The younger the children are vaccinated,the higher the immune response rate will be.Therefore,hepatitis B vaccine should be vaccinated as soon as possible.

hepatitis B virus infectionimmune responseprophylactic vaccinationhepatitis B vaccinehepatitis B virus

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南阳市卧龙区疾控中心 门诊,河南 南阳 473000

免疫应答 乙肝疫苗 预防接种 乙型肝炎病毒

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(5)
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