Observation of the therapeutic Effect and Complications of modified Traction assisted ESD on early gastric Cancer
Objective To explore the therapeutic effect of modified traction assisted endoscopic submucosal dissection(ESD)on early gastric cancer and observe its complications.Methods A total of 60 patients with early gastric cancer admitted to the First Affiliated Hospital of Xinxiang Medical College from January 2017 to June 2022 were selected as the study subjects.They were divided into control group and observation group,with 30 cases in each group,using a random number table method.The control group received traditional ESD treatment,while the observation group received modified traction assisted ESD treatment.The average surgical time,intraoperative bleeding volume,hospitalization time,lesion resection status,lesion start labeling to complete dissection time,mucosal exposure to complete dissection time,serum inflammatory factors[interleukin-6(IL-6),interleukin-8(IL-8),interleukin-12(IL-12)]levels,serum stress hormone[adrenaline(E),norepinephrine(NE),cortisol(Cor)]levels,and postoperative complications were compared between two groups of patients.Results The average surgical time,intraoperative bleeding,and hospitalization time in the observation group were all lower than those in the control group,and the difference was statistically significant(P＜0.05).60 lesions were removed in both groups,and there was no statistically significant difference in the complete lesion removal rate between the observation group and the control group(P＞0.05).The observation group had shorter time from lesion marking to complete dissection and from mucosal exposure to complete dissection compared to the control group,and the differences were statistically significant(P＜0.05).On the 1st day after surgery,the levels of IL-6,IL-8,IL-12,E,NE,and Cor in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Among the 60 patients,3 experienced intraoperative bleeding,all of which were successfully stopped under endoscopy,and there was no uncontrollable large bleeding during the ESD operation;Four cases experienced intraoperative perforation,all of which were small perforations of 3～5 mm.They were clamped with metal clips during the surgery and cured after postoperative treatment;Four patients experienced abdominal pain and bloating after surgery;One case developed infection.The incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Improving traction assisted ESD treatment for early gastric cancer can shorten surgical time,reduce intraoperative bleeding,improve lesion dissection effect,and have high safety.
国家科技期刊平台
NSTL
万方数据
