首页|去骨瓣减压术联合血肿清除术治疗高血压脑出血的疗效观察

去骨瓣减压术联合血肿清除术治疗高血压脑出血的疗效观察

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目的 浅析去骨瓣减压术联合血肿清除术治疗高血压脑出血(HICH)的疗效。方法 选取 2021 年 6 月至2023 年 6 月开封市人民医院收治的 86 例HICH患者的病案资料纳入研究,进行回顾性分析;根据患者的手术方案差异进行分组,其中 43 例患者为对照组,接受血肿清除术治疗;另 43 例患者为观察组,接受去骨瓣减压术联合血肿清除术治疗;观察两组手术指标、并发症、基质金属蛋白酶 9(MMP-9)、白介素-6(IL-6)、C反应蛋白(CRP)、美国国立卫生院卒中量表(NIHSS)、Barthel指数(BI)、Fugl-Meyer评分量表(FMA)、手术有效率及不良预后率差异。结果 (1)观察组手术用时长于对照组,术后 24 h颅内压低于对照组,住院时间短于对照组,手术有效率高于对照组,不良预后率低于对照组,差异有统计学意义(P<0。05);但两组术中失血量、并发症发生率比较,差异无统计学意义(P>0。05)。(2)两组术前MMP-9、IL-6、CRP水平及NIHSS、BI、FMA评分比较,差异无统计学意义(P>0。05);术后观察组MMP-9、IL-6、CRP水平及NIHSS评分均低于对照组,BI、FMA评分高于对照组,差异有统计学意义(P<0。05)。结论 HICH患者接受去骨瓣减压术联合血肿清除术治疗,可有效降低颅内压,改善炎症因子,促进脑部血运重建,更好地恢复神经功能,为患者争取理想预后。
The Efficacy Observation of Decompressive Craniectomy combined with Hematoma Aspiration in the Treatment of Hypertensive Intracerebral Hemorrhage
Objective To analyze the efficacy of decompressive craniectomy combined with hematoma aspiration in the treatment of hypertensive intracerebral hemorrhage(HICH).Methods A total of 86 patients diagnosed with HICH and admitted to Kaifeng People's Hospital between June 2021 and June 2023 were selected for inclusion in the study and analyzed retrospectively.The patients were grouped according to the differences in surgical protocols.The control group,comprising 43 patients,received hematoma debridement,while the observation group,comprising 43 patients,was treated with The surgical protocols included debridement flap decompression,with the observation group receiving hematoma debridement.The surgical indexes were observed in both groups,including complications,matrix metalloproteinase 9(MMP-9),interleukin-6(IL-6),C-reactive protein(CRP),National Institutes of Health Stroke Scale(NIHSS),Barthel Index(BI),Fugl-Meyer Assessment(FMA),surgical efficiency,and poor prognosis.Results(1)The observation group underwent surgery for a longer duration than the control group,exhibited lower postoperative intracranial pressure than the control group,spent a shorter period of time in the hospital than the control group,demonstrated higher surgical efficiency than the control group,and exhibited a lower adverse prognosis rate than the control group(P<0.05).However,there was no statistically significant difference in the comparison of the amount of intraoperative blood loss and the incidence of complications between the two groups(P>0.05).(2)A comparison of preoperative MMP-9,IL-6,CRP levels and NIHSS,BI and FMA scores between the two groups revealed no statistically significant difference(P>0.05).However,postoperative MMP-9,IL-6,CRP levels and NIHSS scores of the observation group were found to be lower than those of the control group,while BI and FMA scores were higher than those of the control group,with a statistically significant difference(P<0.05).Conclusion The combination of debridement,decompression,and hematoma removal has been demonstrated to effectively reduce intracranial pressure,improve inflammatory factors,promote cerebral blood flow reconstruction,and better restore neurological function in patients with intracranial hypertension.This approach has the potential to improve outcomes and strive for an ideal prognosis for patients.

decompressive craniectomyhematoma aspirationhypertensive intracerebral hemorrhage

杨俊杰、刘怡潇、孟凡学

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开封市人民医院 神经外科,河南 开封 475000

去骨瓣减压术 血肿清除术 高血压脑出血

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(6)
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