首页|氟伏沙明联合认知行为疗法治疗儿童青少年情绪障碍的疗效观察

氟伏沙明联合认知行为疗法治疗儿童青少年情绪障碍的疗效观察

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目的 分析氟伏沙明联合认知行为疗法治疗儿童青少年情绪障碍的疗效。方法 将 2020 年 1 月至 2022 年 12月新疆医科大学第一附属医院儿童青少年情绪障碍患儿(100 例)设置为研究对象,按照随机单双数抽签法分组(抽到单数入对照组、抽到双数入研究组),各 50 例,对照组应用单一氟伏沙明治疗,研究组采取氟伏沙明+认知行为疗法治疗。比较两组治疗前后儿童抑郁障碍自评量表(DSRSC)评分、儿童焦虑性情绪障碍筛查表(SCARED)评分、儿童大体评定量表(CGAS)评分及儿童青少年生活质量量表(QLSCA)评分。结果 治疗前两组DSRSC、SCARED评分对比差异无统计学意义(P>0。05),治疗后两组DSRSC、SCARED评分较治疗前均降低,且研究组评估分值低于对照组,差异均有统计学意义(P<0。05);治疗前两组CGAS评分对比差异无统计学意义(P>0。05),治疗后两组CGAS评分较治疗前均升高,且研究组评估分值高于对照组,差异均有统计学意义(P<0。05);治疗前两组QLSCA各维度评分对比差异无统计学意义(P>0。05),治疗后两组QLSCA各维度评分较治疗前均升高,且研究组评估分值高于对照组,差异均有统计学意义(P<0。05)。结论 儿童青少年情绪障碍采用氟伏沙明+认知行为治疗可取得较理想的抗焦虑、抗抑郁的治疗效果,同时可提升生活质量,值得应用。
An Observation of Fluvoxamine and Cognitive Behavioral Therapy in Emotional Disorder Children and Adolescents
Objective To analyze the efficacy of fluvoxamine combined with cognitive-behavioral therapy in treating mood disorders in children and adolescents.Methods A total of 100 cases of children and adolescents with mood disorders were selected from the First Affiliated Hospital of Xinjiang Medical University between January 2020 and December 2022 as subjects for the study.The subjects were grouped according to a random odd-even lottery method.A random number generator was used to determine the allocation of cases into the control and research groups.Each group comprised 50 cases,and the control group received a single fluvoxamine treatment,while the research group received fluvoxamine in combination with cognitive behavioral therapy.The two groups were compared before and after treatment with the scores of the following instruments:the Children's Depression Rating Scale(CDRS),the Screen for Child Anxiety Related Emotional Disorders(SCARED),the Children's Global Assessment Scale(CGAS),and the Children's and Adolescents'Quality of Life Scale(QLSCA).Results The difference between the DSRSC and SCARED scores of the two groups before treatment was not statistically significant(P>0.05).However,the DSRSC and SCARED scores of the two groups after treatment were lower than before treatment.Furthermore,the assessment scores of the research group were lower than those of the control group,and the difference was statistically significant(P<0.05).5)The difference between the CGAS scores of the two groups before treatment was not statistically significant(P>0.05),and after treatment,the CGAS scores of the two groups were higher than before treatment.The assessment scores of the research group were higher than those of the control group,and the differences were statistically significant(P<0.05).The scores of the QLSCA dimensions between the two groups before treatment were not statistically significant(P>0.05).However,the scores of the QLSCA dimensions of the two groups after treatment were higher than those of the pre-treatment period.Furthermore,the assessment scores of the research group were higher than those of the control group,and the differences were all statistically significant(P<0.05).Conclusion The combination of fluvoxamine and cognitive-behavioral therapy for mood disorders in children and adolescents has been demonstrated to result in superior therapeutic outcomes for both anxiety and depression,while simultaneously enhancing quality of life.This approach is therefore worthy of further investigation.

fluvoxaminecognitive behavioral therapyemotional disorder in children and adolescents

丽扎·满苏尔、罗晓

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新疆医科大学第一附属医院 心理医学中心,新疆 乌鲁木齐 830054

氟伏沙明 认知行为治疗 儿童青少年情绪障碍

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(6)
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