Value Analysis of Serum IL-6 and Pepsinogen Ⅰ/Ⅱ Ratio on the Prognosis Assessment for Elderly Gastric Cancer Patients
Objective To discuss the clinical value of serum interleukin-6(IL-6)and pepsinogen Ⅰ/Ⅱ(PGⅠ/Ⅱ)on the prognosis assessment for elderly gastric cancer patients.Methods A total of 75 elderly gastric cancer patients treated from May 2020 to May 2021 in Yongmei Group General Hospital were reviewed.PGⅠ/Ⅱ and IL-6 values were measured through the latex-enhanced immunoturbidimetry and magnetic particle chemiluminescence method.Logistic regression equation was used to analyze the risk factors of the elderly gastric cancer patient's clinical prognosis.The clinical value of serum IL-6 and PGⅠ/Ⅱon the assessment of surgical prognosis was studied.Results Till May 2023,75 patients have been followed up with no missing individuals.Patients were followed for 20～30 months,with an average value of(25.63±3.25)months.After follow-up,there were a total of 29 patients with poor prognosis,with an incidence rate of 38.67%,and they were designated as the poor prognosis group;A total of 46 patients with good prognosis were designated as the group with good prognosis;The results of univariate analysis showed that histological differentiation,TNM stages,IL-6 levels and PG Ⅰ/Ⅱ values were statistically significant factors affecting the prognosis of elderly gastric cancer patients(P＜0.05);there were no correlations with the patient's age,tumor size,complicated disease and education background,and the differences were not statistically significant(P＞0.05);the multivariate Logistic regression equation showed that histological differentiation,TNM staging,IL-6,and PGⅠ/Ⅱ ratio were all statistically significant risk factors for poor prognosis of elderly gastric cancer(P＜0.05).Conclusion The ratio of serum IL-6 to PGⅠ/Ⅱ can predict the prognosis of elderly gastric cancer patients and has important value.
国家科技期刊平台
NSTL
万方数据
