Study on the Characteristics of Postnatal Blood Oxygen Saturation and the Morphology and Function of Red Blood Cells in Healthy Newborns in Ali District,Xizang Autonomous Region
Objective To explore the characteristics of postnatal SpO2 level,erythrocyte morphology and function of newborns in Ali,Xizang Autonomous Region,by comparing the SpO2 level and blood routine test level of healthy newborns in Ali People's Hospital and two hospitals in Shaanxi Province.Methods This study is a blind retrospective study.167 full-term newborns born normally from January 2020 to July 2020 were selected from the People's Hospital of Ali Region,People's Hospital of Jingyang County,and Department of Neonatology of Yaozhou District People's Hospital.74 newborns born in the People's Hospital of Ali Region were selected as the plateau group,and 93 newborns born in two hospitals in Shaanxi Province were selected as the plain group.SpO2 and heart rate of right upper limb were monitored 10 min after umbilical cord amputation,and discarded umbilical blood was collected for blood cell analysis.The characteristics of SpO2 levels of full-term normal newborns at 10 minutes after birth between plateau group and plain group were compared,and compare them with the target SpO2 values in the Newborn Resuscitation Guidelines(2021)(hereinafter referred to as the Guidelines).At the same time,the difference of blood cell analysis between the two groups was compared.Results The SpO2 levels of newborns born in the high-altitude group were lower than those in the plain group at 1～10 minutes of birth,and the difference was statistically significant(P＜0.05).The cord blood white blood cell count and platelet count of newborns born in the high-altitude group were lower than those in the plain group,and the difference was statistically significant(P＜0.05);The red blood cell count and hemoglobin were higher than those in the plain group,and the difference was statistically significant(P＜0.05);The average volume of red blood cells was smaller than that of the plain group,and the difference was statistically significant(P＜0.05).The average hemoglobin volume,average hemoglobin concentration,standard deviation of red blood cell distribution width,and coefficient of variation of red blood cell distribution width were higher than those of the plain group,and the difference was statistically significant(P＜0.05).The compliance rate between the SpO2 levels of newborns born in the plateau group at 1～8 minutes and the target values of the guidelines was significantly lower than that in the plain group,and the difference was statistically significant(P＜0.05).Newborns born in the high-altitude group at 9 minutes and 10 minutes after birth,the compliance rate between the SpO2 level and the target value of the guidelines is 100%,and there is no statistically significant difference compared to the plain group(P＞0.05).Conclusion The expected value of SpO2 at 10 min after birth in the Guidelines is suitable for newborns in Ali area of Xizang autonomous region.The unique morphology of cord blood red blood cells and high hemoglobin content and concentration may be one of the reasons for Tibetan newborns to adapt to plateau.
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