首页|高血压及冠心病患者和健康体检者血脂检验结果的比较研究

高血压及冠心病患者和健康体检者血脂检验结果的比较研究

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目的 观察心血管病患者和健康人群之间的血脂水平差异,并分析导致血脂异常的影响因素。方法 将平顶山市第一人民医院 2020 年 1 月至 2023 年 12 月在体检科进行体检的 164 例受检者作为研究对象进行回顾性研究,收集受检者的血脂检查报告及其他一般资料。根据影响受检者血脂异常的因素,将其中 82 例已确诊心血管病的患者纳入观察组,另外82例健康体检者纳入对照组,比较两组之间的总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白B(Apo-B)水平差异;再根据 82 例心血管病患者的疾病种类不同,将其细分为高血压组 30 例、冠心病组 21 例、高血压合并冠心病组 31 例,比较三组之间的TC、TG、LDL-C、HDL-C、Apo-B水平差异;对比对照组与观察组之间的年龄、性别、受教育情况、体质量指数(BMI)、婚姻情况、吸烟情况、饮酒情况、锻炼情况,并将单因素分析有意义的变量纳入多因素Logistic回归分析中,识别血脂异常的独立危险因素。结果 (1)观察组TC、TG、LDL-C、Apo-B水平高于对照组,HDL-C水平低于对照组,差异有统计学意义(P<0。05)。(2)高血压组、冠心病组、高血压合并冠心病之间的TC、TG、LDL-C、HDL-C、Apo-B水平比较,差异有统计学意义(P<0。05);其中高血压合并冠心病组的TC、TG、LDL-C、Apo-B水平高于冠心病组和高血压组,HDL-C水平低于冠心病组和高血压组,差异有统计学意义(P<0。05)。(3)年龄≥60 岁、BMI≥28 kg/m2、吸烟、饮酒、锻炼<3 次/周是血脂异常的独立危险因素。结论 心血管病患者存在一定程度的血脂异常,其中高血压合并冠心病患者的血脂异常情况较单一高血压和冠心病患者更加突出;血脂异常的独立危险因素众多,医方需要加强对血脂异常风险人群的管理,预防发生心血管病。
Comparative Study on Blood Lipid Test Results of Hypertension and Coronary Heart Disease Patients and Healthy Examinees
Objective To observe the difference in blood lipid levels between cardiovascular disease patients and healthy people,and to analyze the influencing factors leading to abnormal blood lipids.Methods A retrospective study was conducted on 164 examinees who underwent physical examination in the Department of Physical Examination of The First People's Hospital of Pingdingshan from January 2020 to December 2023,and their blood lipid test reports and other general information were collected.According to the factors affecting the abnormal blood lipids of the examinees,82 patients who had been diagnosed with cardiovascular diseases were included in the observation group,and another 82 healthy examinees were included in the control group.The differences in total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),and apolipoprotein B(Apo-B)levels between the two groups were compared.Then,according to the different types of diseases of the 82 cardiovascular disease patients,they were further divided into a hypertension group of 30 cases,a coronary heart disease group of 21 cases,and a hypertension combined with coronary heart disease group of 31 cases.The differences in TC,TG,LDL-C,HDL-C,and Apo-B levels among the three groups were compared.The age,gender,education level,body mass index(BMI),marital status,smoking status,drinking status,and exercise status between the control group and the observation group were compared,and the variables with significance in univariate analysis were included in the multivariate Logistic regression analysis to identify the independent risk factors for abnormal blood lipids.Results(1)The TC,TG,LDL-C,and Apo-B levels in the observation group were higher than those in the control group,and the HDL-C level was lower than that in the control group,with a statistically significant difference(P<0.05).(2)There was a statistically significant difference in the comparison of TC,TG,LDL-C,HDL-C,and Apo-B levels among the hypertension group,coronary heart disease group,and hypertension combined with coronary heart disease group(P<0.05).Among them,the TC,TG,LDL-C,and Apo-B levels in the hypertension combined with coronary heart disease group were higher than those in the coronary heart disease group and hypertension group,and the HDL-C level was lower than those in the coronary heart disease group and hypertension group,with a statistically significant difference(P<0.05).(3)Age≥60 years old,BMI≥28 kg/m2,smoking,drinking,and exercising<3 times/week are independent risk factors for abnormal blood lipids.Conclusion Cardiovascular disease patients have a certain degree of abnormal blood lipids,among which the abnormal blood lipids of patients with hypertension combined with coronary heart disease are more prominent than those with single hypertension and coronary heart disease.There are many independent risk factors for abnormal blood lipids,and doctors need to strengthen the management of people at risk of abnormal blood lipids to prevent the occurrence of cardiovascular diseases.

hypertensioncoronary heart diseaseblood lipidsinfluencing factors

牛露媛

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平顶山市第一人民医院 健康管理中心,河南 平顶山 467000

高血压 冠心病 血脂 影响因素

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(6)
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