Comparative Study on Blood Lipid Test Results of Hypertension and Coronary Heart Disease Patients and Healthy Examinees
Objective To observe the difference in blood lipid levels between cardiovascular disease patients and healthy people,and to analyze the influencing factors leading to abnormal blood lipids.Methods A retrospective study was conducted on 164 examinees who underwent physical examination in the Department of Physical Examination of The First People's Hospital of Pingdingshan from January 2020 to December 2023,and their blood lipid test reports and other general information were collected.According to the factors affecting the abnormal blood lipids of the examinees,82 patients who had been diagnosed with cardiovascular diseases were included in the observation group,and another 82 healthy examinees were included in the control group.The differences in total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),and apolipoprotein B(Apo-B)levels between the two groups were compared.Then,according to the different types of diseases of the 82 cardiovascular disease patients,they were further divided into a hypertension group of 30 cases,a coronary heart disease group of 21 cases,and a hypertension combined with coronary heart disease group of 31 cases.The differences in TC,TG,LDL-C,HDL-C,and Apo-B levels among the three groups were compared.The age,gender,education level,body mass index(BMI),marital status,smoking status,drinking status,and exercise status between the control group and the observation group were compared,and the variables with significance in univariate analysis were included in the multivariate Logistic regression analysis to identify the independent risk factors for abnormal blood lipids.Results(1)The TC,TG,LDL-C,and Apo-B levels in the observation group were higher than those in the control group,and the HDL-C level was lower than that in the control group,with a statistically significant difference(P<0.05).(2)There was a statistically significant difference in the comparison of TC,TG,LDL-C,HDL-C,and Apo-B levels among the hypertension group,coronary heart disease group,and hypertension combined with coronary heart disease group(P<0.05).Among them,the TC,TG,LDL-C,and Apo-B levels in the hypertension combined with coronary heart disease group were higher than those in the coronary heart disease group and hypertension group,and the HDL-C level was lower than those in the coronary heart disease group and hypertension group,with a statistically significant difference(P<0.05).(3)Age≥60 years old,BMI≥28 kg/m2,smoking,drinking,and exercising<3 times/week are independent risk factors for abnormal blood lipids.Conclusion Cardiovascular disease patients have a certain degree of abnormal blood lipids,among which the abnormal blood lipids of patients with hypertension combined with coronary heart disease are more prominent than those with single hypertension and coronary heart disease.There are many independent risk factors for abnormal blood lipids,and doctors need to strengthen the management of people at risk of abnormal blood lipids to prevent the occurrence of cardiovascular diseases.