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妊娠期糖尿病患者自发性早产的危险因素分析

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目的 分析妊娠期糖尿病(GDM)患者自发性早产(SPB)的危险因素。方法 选取 2020 年 1 月至 2024 年1 月在虞城县第二人民医院接受治疗的 108 例GDM患者的临床资料进行回顾性分析,根据是否出现SPB分为对照组(n=90)与早产组(n=18),统计两组临床资料,进行单因素与多因素Logistic回归分析,明确GDM患者SPB发生的危险因素。结果 早产组妊娠年龄大于对照组,孕前体质量指数(BMI)更高,差异均有统计学意义(P<0。05),自然流产史、胎膜早破(PROM)、高血压、糖尿病家族史、妊娠期感染史均占比更高,差异均有统计学意义(P<0。05);多因素Logistic回归分析结果显示,妊娠年龄大(OR=2。031)、孕前BMI高(OR=3。112)、自然流产史(OR=1。765)、PROM(OR=2。436)、高血压(OR=2。842)、糖尿病家族史(OR=5。132)、妊娠期感染史(OR=1。946)是GDM患者SPB发生的独立危险因素,差异均有统计学意义(P<0。05)。结论 GDM患者可能引起SPB,妊娠年龄、孕前BMI、自然流产史、PROM、高血压、糖尿病家族史、妊娠期感染史均为GDM患者发生SPB的危险因素。
Analysis of Risk Factors for Spontaneous Preterm Birth in Patients with Gestational Diabetes Mellitus
Objective To analyze the risk factors for spontaneous preterm birth(SPB)in patients with gestational diabetes mellitus(GDM).Methods The clinical data of 108 GDM patients treated in Yucheng County Second People's Hospital from January 2020 to January 2024 were retrospectively analyzed.According to whether SPB occurred,they were divided into the control group(n=90)and the preterm birth group(n=18).The clinical data of the two groups were statistically analyzed,and univariate and multivariate logistic regression analyses were performed to clarify the risk factors for SPB in GDM patients.Results The maternal age of the preterm birth group was older than that of the control group,and the pre-pregnancy body mass index(BMI)was higher,with statistically significant differences(P<0.05).The proportions of natural abortion history,premature rupture of membranes(PROM),hypertension,family history of diabetes,and history of infection during pregnancy were all higher,with statistically significant differences(P<0.05).The Results of multivariate logistic regression analysis showed that older maternal age(OR=2.031),higher pre-pregnancy BMI(OR=3.112),natural abortion history(OR=1.765),PROM(OR=2.436),hypertension(OR=2.842),family history of diabetes(OR=5.132),and history of infection during pregnancy(OR=1.946)were independent risk factors for SPB in GDM patients,with statistically significant differences(P<0.05).Conclusion GDM patients may cause SPB.Maternal age,pre-pregnancy BMI,natural abortion history,PROM,hypertension,family history of diabetes,and history of infection during pregnancy are all risk factors for SPB in GDM patients.

gestational diabetes mellitusspontaneous preterm birthrisk factors

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虞城县第二人民医院 妇产科,河南 商丘 476300

妊娠期糖尿病 自发性早产 危险因素

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(7)