The Application Effect of Methylergometrine Maleate Combined with Carboprost Tromethamine Injection in Preventing Postpartum Hemorrhage
Objective To explore the application effect of methylergometrine maleate combined with carboprost tromethamine injection in preventing postpartum hemorrhage.Methods The research subjects were selected from 86 parturients who gave birth in The Second People's Hospital of Jiaozuo from March 2022 to February 2023.They were divided into a control group and an observation group,with 43 cases in each group,and the grouping method was the random number table method.On the basis of routine symptomatic treatment,the control group was treated with carboprost tromethamine,and the observation group was given methylergometrine maleate on the basis of the control group.The clinical efficacy,recovery situation,coagulation function,and adverse reactions of the two groups of patients were compared.Results The treatment effectiveness rate of the observation group 2 hours after delivery(95.35%)was higher than that of the control group(74.42%),and the difference was statistically significant(P＜0.05).Compared with the control group,the speed of uterine bottom drop in the observation group was relatively faster,the duration of lochia in the observation group was relatively shorter,and the amount of bleeding 2 hours and 24 hours after delivery was relatively less,and the differences were statistically significant(P＜0.05).The levels of plasma D-dimer(D-D)and fibrinogen(FIB)in the two groups were lower 24 hours after surgery than before surgery,and the observation group was relatively lower than the control group.The prothrombin time(PT)and activated partial thromboplastin time(APTT)were shortened compared with before surgery,and the observation group was relatively shorter than the control group,and the differences were statistically significant(P＜0.05).During the research period,there was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The application effect of methylergometrine maleate combined with carboprost tromethamine injection in preventing postpartum hemorrhage in parturients is good,the speed of uterine bottom drop is relatively faster,the duration of lochia is shorter,and the amount of bleeding 2 hours and 24 hours after delivery is relatively less,while improving coagulation function,and the safety of combined medication is high.
国家科技期刊平台
NSTL
万方数据
