首页|右美托咪定辅助全身麻醉对肺部分切除术患者血流动力学的影响

右美托咪定辅助全身麻醉对肺部分切除术患者血流动力学的影响

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目的 探讨右美托咪定辅助全身麻醉对肺部分切除术患者血流动力学的影响。方法 选取 2022 年 5 月至2023 年 12 月许昌市人民医院收治的 60 例肺部分切除术患者作为研究对象,采用随机数表法将其分为对照组和观察组,每组均 30 例,对照组采取常规全身麻醉,观察组进行右美托咪定辅助全身麻醉。比较两组不同时段下血流动力学指数变化、并发症发生率、不良反应发生率、麻药用量以及血管活性药应用人次。结果 观察组围术期、手术完成阶段、术后 30 min心率、平均动脉压低于同时段对照组,血氧饱和度高于同时段对照组,差异均有统计学意义(P<0。05);观察组不良反应发生率和并发症发生率均低于对照组,差异均有统计学意义(P<0。05);观察组血管活性药应用人次显著少于对照组,麻醉药用量低于对照组,差异均有统计学意义(P<0。05)。结论 通过采取右美托咪定辅助全身麻醉,对于肺部分切除术患者血流动力学影响较小,有效减少麻醉药剂用量及并发症,值得临床应用。
The Impact of Dexmedetomidine-assisted General Anesthesia on Hemodynamics in Patients Undergoing Pulmonary Lobectomy
Objective To investigate the impact of dexmedetomidine-assisted general anesthesia on hemodynamics in patients undergoing pulmonary lobectomy.Methods Sixty patients who underwent pulmonary lobectomy in Xuchang People's Hospital from May 2022 to December 2023 were selected as the research subjects.They were randomly divided into a control group and an observation group,with 30 cases in each group.The control group received conventional general anesthesia,while the observation group received dexmedetomidine-assisted general anesthesia.The changes in hemodynamic indices at different time periods,the incidence of complications,the incidence of adverse reactions,the amount of anesthetic used,and the number of uses of vasoactive drugs were compared between the two groups.Results The heart rate and mean arterial pressure of the observation group were lower than those of the control group at the perioperative period,the completion stage of the operation,and 30 minutes after the operation,and the blood oxygen saturation was higher than that of the control group at the same time period,with statistically significant differences(P<0.05).The incidence of adverse reactions and complications in the observation group was lower than that in the control group,with statistically significant differences(P<0.05).The number of uses of vasoactive drugs in the observation group was significantly less than that in the control group,and the amount of anesthetic used was lower than that in the control group,with statistically significant differences(P<0.05).Conclusion By adopting dexmedetomidine-assisted general anesthesia,the impact on hemodynamics in patients undergoing pulmonary lobectomy is small,effectively reducing the amount of anesthetic and complications,and is worth clinical application.

dexmedetomidinegeneral anesthesiahemodynamics

李瑞峰、韩孟阳

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许昌市人民医院 麻醉科手术部,河南 许昌 461000

右美托咪定 全身麻醉 血流动力学

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(7)