Observation of the Effect of Banxia Houpo Decoction Combined with Omeprazole in the Treatment of Gastroesophageal Reflux Disease
Objective To explore the effect of Banxia Houpo decoction combined with omeprazole in the treatment of gastroesophageal reflux disease(GERD).Methods A total of 102 patients with GERD treated in Xinyang People's Hospital from January 2021 to January 2023 were selected.They were divided into the control group(omeprazole)and the research group(omeprazole combined with Banxia Houpo decoction)with 51 cases each using the random number table method.The TCM syndrome scores,gastrointestinal hormones,intestinal flora,clinical efficacy,and adverse reactions of the two groups were compared.Results After treatment,the scores of acid reflux,belching,nocturnal cough,pharyngeal sputum obstruction,chest discomfort,and dysphagia in both groups decreased,and the research group was lower than the control group,with statistically significant differences(P＜0.05).After treatment,the levels of gastrin and gastric growth factor in both groups increased,and the research group was higher than the control group,with statistically significant differences(P＜0.05).After treatment,the number of enterococci and enterobacteria in both groups decreased,and the research group was lower than the control group,with statistically significant differences(P＜0.05);the number of bifidobacteria and lactobacilli in both groups increased,and the research group was more than the control group,with statistically significant differences(P＜0.05).The clinical effective rate of the research group was higher than that of the control group,with statistically significant differences(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion GERD patients receiving Banxia Houpo decoction combined with omeprazole have significant effects,can regulate intestinal flora,improve gastrointestinal hormone levels,and have high safety.
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