Clinical Efficacy of Montelukast Sodium Tablets Combined with Azithromycin Injection in the Treatment of Mycoplasma Pneumonia in Children
Objective To explore the effect of Montelukast Sodium Tablets combined with Azithromycin Injection in the treatment of children with Mycoplasma pneumonia.Methods The cases were selected from June 2020 to June 2023,and 86 children with Mycoplasma pneumonia treated in Fengqiu County Maternal and Child Health Hospital during this period were selected as the research subjects.They were divided into two groups by random number table method.43 children who received Azithromycin Injection alone were set as the control group,and another 43 children who received Montelukast Sodium Tablets combined with Azithromycin Injection were set as the experimental group.The clinical treatment effects,inflammatory factors[C-reactive protein(CRP),lactate dehydrogenase(LDH),and serum ferritin(SF)],imaging examination results,symptom(fever,cough,and lung rales)disappearance time,and safety of the two groups were compared.Results Compared with the control group,the treatment effectiveness rate of the experimental group was higher,and the symptom disappearance time was shortened,with statistically significant differences(P＜0.05).Before treatment,there was no statistical significance in the comparison of inflammatory factor levels between the two groups(P＞0.05).After treatment,the levels of inflammatory factors in both groups decreased,and the experimental group was lower than the control group,with statistically significant differences(P＜0.05).There was no statistical significance in the comparison of adverse reaction incidence between the two groups(P＞0.05).The imaging examination results showed that the incidence of pleural effusion,pleural thickening,atelectasis,and consolidation in the experimental group was lower than that in the control group,with statistically significant differences(P＜0.05).Conclusion After children with Mycoplasma pneumonia receive Montelukast Sodium Tablets combined with Azithromycin Injection,their treatment effect is improved,the level of inflammatory factors is reduced,the symptom disappearance time is shortened,and it is safe and reliable,which is worth using in clinical practice.
万方数据
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