Analysis of Long-term Prognosis and Risk Factors of Patients with Non-small Cell Lung Cancer Undergoing Total Thoracoscopic Lobectomy
Objective To investigate the long-term prognosis and risk factors of patients with non-small cell lung cancer(NSCLC)undergoing total thoracoscopic lobectomy.Methods A retrospective analysis was conducted on the clinical data of 84 patients with NSCLC who underwent total thoracoscopic lobectomy at The First People's Hospital of Xinxiang from January 2017 to January 2020.The surgical conditions of the patients were analyzed,and the survival and recurrence rates were calculated.The clinicopathological characteristics of NSCLC patients were analyzed,and univariate and multivariate analyses were used to identify factors affecting the long-term prognosis of patients.Results All patients were followed up,with a median follow-up time of 30 months,and 4 cases were lost to follow-up.Among the 80 patients,59 survived and 21 died.The 5-year disease-free survival rate was 62.50%(50/80),the overall survival rate was 73.75%(59/80),and the recurrence rate was 11.25%(9/80).Univariate analysis showed that the total number of lymph node dissections,vascular invasion,and T stage were significantly different between the survival and death groups(P＜0.05).Multivariate analysis showed that the total number of lymph node dissections(OR=4.625,95%CI:4.455～4.707),vascular invasion(OR=3.746,95%CI:3.711～3.784),and T stage(OR=2.390,95%CI:1.988～2.796)were factors affecting the prognosis of NSCLC patients,with statistically significant differences(P＜0.05).Conclusion The prognosis of NSCLC patients undergoing total thoracoscopic lobectomy is mainly related to the total number of lymph node dissections,vascular invasion,and T stage.It is necessary to follow up and monitor NSCLC patients,detect recurrence and metastasis in time,and take effective measures to improve patient survival rates.
万方数据
维普
