Analysis of the Value of C-Reactive Protein,Gal-13,and Glycated Hemoglobin in Early Prediction of gestational diabetes mellitus in Early Pregnancy
Objective To explore the clinical value of C-reactive protein(CRP),Galectin-13(Gal-13),and Glycated hemoglobin A1c(HbA1c)in predicting gestational diabetes mellitus in early pregnancy.Methods The clinical data of 98 pregnant women who were registered and underwent prenatal examination in the outpatient clinic of Xihua County Maternal and Child Health Hospital from May 2017 to May 2023 were retrospectively analyzed.According to whether they had gestational diabetes mellitus,they were divided into two groups:the observation group(48 cases)with gestational diabetes mellitus and the control group(50 cases)without gestational diabetes mellitus.The levels of serum CRP,Gal-13,and HbA1c in the two groups of pregnant women were compared,the risk factors affecting the occurrence of gestational diabetes mellitus were analyzed,and the predictive value of serum CRP,Gal-13,and HbA1c for gestational diabetes mellitus was explored.Results The BMI,CRP,and HbA1c levels of the observation group were higher than those of the control group,and Gal-13 was lower than that of the control group,and the difference was statistically significant(P＜0.05).Higher levels of CRP and HbA1c and lower expression levels of Gal-13 were all factors affecting the occurrence of gestational diabetes mellitus(P＜0.05).The area under the curve(AUC)of the receiver operating characteristic(ROC)curve for the combined detection of serum CRP,Gal-13,and HbA1c for gestational diabetes mellitus was higher than that of single detection(Z=2.547,3.676,2.101,P＜0.05).Conclusion Serum CRP,Gal-13,and HbA1c are all factors affecting the occurrence of gestational diabetes mellitus,and they can all be used as predictive indicators for gestational diabetes mellitus.
万方数据
维普
