Clinical Effect of Xiaoyan Lidan Decoction in the Treatment of Severe Acute Pancreatitis of Hepatobiliary Damp-Heat Type
Objective To explore the clinical effect of Xiaoyan Lidan Decoction in the treatment of severe acute pancreatitis(SAP)patients of hepatobiliary damp-heat type.Methods 60 patients with hepatobiliary damp-heat type SAP treated in Xinyang People's Hospital from August 2020 to August 2023 were selected and divided into a control group(n=30)and a research group(n=30)by random number table method.The control group was treated with ursodeoxycholic acid,and the research group was treated with Xiaoyan Lidan Decoction combined with ursodeoxycholic acid.The clinical efficacy,symptom improvement time,traditional Chinese medicine syndrome score,gastrointestinal function[Gastrointestinal Symptom Rating Scale(GSRS)],and adverse reactions of the two groups were compared.Results The effective rate of treatment in the research group(93.33%)was higher than that in the control group(70.00%),with a statistically significant difference(P＜0.05).The disappearance time of abdominal pain,bloating,recovery of bowel sounds,and recovery time of serum amylase in the research group were all shorter than those in the control group,with statistically significant differences(P＜0.05).After treatment,the traditional Chinese medicine syndrome scores of both groups decreased,and the scores of the research group were lower than those of the control group,with statistically significant differences(P＜0.05).After treatment,the GSRS scores of both groups decreased,and the GSRS score of the research group was lower than that of the control group,with statistically significant differences(P＜0.05).The incidence of adverse reactions in the research group(10.00%)was lower than that in the control group(36.67%),with a statistically significant difference(P＜0.05).Conclusion The application of Xiaoyan Lidan Decoction in the treatment of hepatobiliary damp-heat type SAP patients can improve the clinical efficacy,shorten the symptom improvement time,reduce the traditional Chinese medicine syndrome score,improve gastrointestinal function,and reduce adverse reactions.
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