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麝香保心丸联合硝酸异山梨酯对老年冠心病心绞痛患者的影响

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目的 探讨老年冠心病心绞痛患者采用麝香保心丸联合硝酸异山梨酯治疗对临床疗效、心绞痛发作情况、心功能的影响。方法 选取 2021 年 3 月至 2022 年 3 月固始县人民医院内科收治的 86 例老年冠心病心绞痛患者,按照随机数字表法分成治疗组(n=43)与对照组(n=43),对照组采用硝酸异山梨酯治疗,治疗组采用麝香保心丸联合硝酸异山梨酯治疗,比较两组临床疗效、症状评分、心绞痛发作情况及心功能情况。结果 治疗组治疗有效率(95。35%)高于对照组(79。07%),差异具有统计学意义(P<0。05);治疗后两组症状(心悸、气短、胸闷、胸痛)评分低于治疗前,且治疗组症状评分低于对照组,差异具有统计学意义(P<0。05);治疗后两组心绞痛发作持续时间短于治疗前,发作频率低于治疗前,且治疗组心绞痛发作持续时间短于对照组,发作频率低于对照组,差异具有统计学意义(P<0。05);治疗后两组左心室射血分数(LVEF)、心输出量(CO)水平高于治疗前,左心室舒张末期内径(LVEDD)水平低于治疗前,且治疗组LVEF、CO水平高于对照组,LVEDD水平低于对照组,差异具有统计学意义(P<0。05)。结论 麝香保心丸联合硝酸异山梨酯应用于老年冠心病心绞痛患者治疗中,能够提高临床疗效,促进临床症状缓解,改善心绞痛发作情况及心功能。
The Impact of Shexiang Baoxin Pill Combined with Isosorbide Nitrate on Elderly Patients with Coronary Heart Disease and Angina Pectoris
Objective To explore the clinical efficacy,angina attack,and cardiac function of elderly patients with coronary heart disease and angina pectoris treated with Shexiang Baoxin Pill combined with Isosorbide Nitrate.Methods 86 elderly patients with coronary heart disease and angina pectoris admitted to the Department of Internal Medicine of Gushi County People's Hospital from March 2021 to March 2022 were selected.According to the random number table method,they were divided into a treatment group(n=43)and a control group(n=43).The control group was treated with Isosorbide Nitrate,and the treatment group was treated with Shexiang Baoxin Pill combined with Isosorbide Nitrate.The clinical efficacy,symptom scores,angina attack,and cardiac function of the two groups were compared.Results The effective rate of treatment in the treatment group(95.35%)was higher than that in the control group(79.07%),and the difference was statistically significant(P<0.05).After treatment,the symptom scores(palpitations,shortness of breath,chest tightness,chest pain)of the two groups were lower than before treatment,and the symptom scores of the treatment group were lower than those of the control group,and the difference was statistically significant(P<0.05).After treatment,the duration of angina attack and the frequency of attack in the two groups were shorter than before treatment,and the duration of angina attack and the frequency of attack in the treatment group were shorter than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the left ventricular ejection fraction(LVEF)and cardiac output(CO)levels of the two groups were higher than before treatment,and the left ventricular end-diastolic diameter(LVEDD)level was lower than before treatment.The LVEF and CO levels of the treatment group were higher than those of the control group,and the LVEDD level was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The application of Shexiang Baoxin Pill combined with Isosorbide Nitrate in the treatment of elderly patients with coronary heart disease and angina pectoris can improve the clinical efficacy,promote the relief of clinical symptoms,improve the angina attack and cardiac function.

coronary heart diseaseangina pectorisShexIang BAoxiN PiLlisosorbide nitratecardiac function

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固始县人民医院 心血管内科二病区,河南 信阳 465200

冠心病 心绞痛 麝香保心丸 硝酸异山梨酯 心功能

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(8)