The Impact of Reduning Injection Combined with Nebulized Budesonide Suspension on Patients with Acute Exacerbation of Chronic Bronchitis
Objective To analyze the effect of Reduning Injection combined with nebulized budesonide suspension on the clinical symptoms and inflammatory factor levels of patients with acute exacerbation of chronic bronchitis.Methods From January 2019 to August 2023,60 patients with acute exacerbation of chronic bronchitis treated in Xinzheng Huaxin Minsheng Hospital were selected.According to the random number table method,the patients were divided into a control group(given nebulized budesonide suspension treatment)and a combination group(using Reduning Injection on the basis of the control group),with 30 patients in each group.Both groups were treated continuously for 7 days.The clinical efficacy of the two groups of patients,the improvement time of clinical symptoms after treatment,the changes in serum inflammatory factor levels before and after treatment,blood gas indicators,and adverse reactions were compared.Results The treatment effectiveness rate of the combination group(93.33%)was higher than that of the control group(73.33%),and the difference was statistically significant(P＜0.05);the improvement time of fever,dyspnea,wheezing cough,and pulmonary X-ray inflammatory absorption symptoms in the combination group was significantly shorter than that in the control group,and the difference was statistically significant(P＜0.05);after 7 days of treatment,the serum inflammatory factor level of the combination group was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05);after 7 days of treatment,the arterial oxygen partial pressure(PaO2)and oxygen saturation(SaO2)levels of the combination group were significantly higher than those of the control group,and the partial pressure of carbon dioxide(PaCO2)was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05);the incidence rate of adverse reactions in the combination group(13.33%)was compared with the control group(16.67%),and the difference was not statistically significant(P＞0.05).Conclusion Reduning Injection combined with nebulized budesonide suspension treatment for patients with acute exacerbation of chronic bronchitis has a good clinical effect,can significantly reduce the inflammatory response in the patient's body,improve blood gas indicators,and shorten the symptom improvement time.
Reduning Injectionnebulized budesonide suspensionacute exacerbation of chronic bronchitisclinical symptomsinflammatory factors
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维普
