首页|雷珠单抗联合复方血栓通胶囊在视网膜静脉阻塞患者中的应用效果分析

雷珠单抗联合复方血栓通胶囊在视网膜静脉阻塞患者中的应用效果分析

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目的 探讨雷珠单抗联合复方血栓通胶囊在视网膜静脉阻塞(RVO)患者中的应用效果。方法 选取 2021 年4月至2022年4月河南省濮阳市范县复明医院收治的66例RVO患者,按数字表法随机分为联合组(33例)和对照组(33例),对照组采用雷珠单抗治疗,联合组给予雷珠单抗联合复方血栓通胶囊治疗。对比两组疗效、治疗前后最佳矫正视力水平、视网膜黄斑厚度及复发情况。结果 联合组治疗有效率(96。97%)高于对照组(78。79%),差异具有统计学意义(P<0。05);两组治疗后最佳矫正视力水平高于治疗前,且联合组高于对照组,差异均有统计学意义(P<0。05);两组治疗后视网膜黄斑厚度低于治疗前,且联合组低于对照组,差异均有统计学意义(P<0。05);联合组RVO复发率(3。03%)低于对照组(18。18%),差异具有统计学意义(P<0。05)。结论 雷珠单抗联合复方血栓通胶囊治疗RVO疗效理想,有助于提高患者最佳矫正视力,降低视网膜黄斑厚度和RVO复发率。
Analysis of the Application Effect of Ranibizumab Monoclonal Antibody Combined with Compound Thrombus Capsules in Patients with Retinal Vein Occlusion
Objective To explore the application effect of ranibizumab monoclonal antibody combined with compound thrombus capsules in patients with retinal vein occlusion(RVO).Methods 66 RVO patients admitted to Fuming Hospital in Fan County,Puyang City,Henan Province from April 2021 to April 2022 were selected and randomly divided into a combination group(33 cases)and a control group(33 cases)according to the digital table method.The control group was treated with ranibizumab monoclonal antibody,and the combination group was given ranibizumab monoclonal antibody combined with compound thrombus capsules.The therapeutic effects,best corrected visual acuity level before and after treatment,retinal macular thickness,and recurrence situation of the two groups were compared.Results The effective rate of treatment in the combination group(96.97%)was higher than that in the control group(78.79%),and the difference was statistically significant(P<0.05).The best corrected visual acuity level after treatment in both groups was higher than before treatment,and the combination group was higher than the control group,and the differences were statistically significant(P<0.05).The retinal macular thickness after treatment in both groups was lower than before treatment,and the combination group was lower than the control group,and the differences were statistically significant(P<0.05).The RVO recurrence rate in the combination group(3.03%)was lower than that in the control group(18.18%),and the difference was statistically significant(P<0.05).Conclusion The treatment of RVO with ranibizumab monoclonal antibody combined with compound thrombus capsules has an ideal effect,which can help improve the best corrected visual acuity of patients,reduce retinal macular thickness,and RVO recurrence rate.

retinal vein occlusionranibizumab monoclonal antibodycompound thrombus capsulesbest corrected visual acuity

吕东伟、吕金华

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河南省濮阳市范县复明医院 眼科,河南 濮阳 457000

视网膜静脉阻塞 雷珠单抗 复方血栓通胶囊 最佳矫正视力

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(8)