首页|荧光引导技术结合多模态影像神经导航在脑胶质瘤中的应用效果

荧光引导技术结合多模态影像神经导航在脑胶质瘤中的应用效果

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目的 分析荧光引导技术结合多模态影像神经导航在脑胶质瘤中的应用效果及对神经功能、肿瘤复发率的影响。方法 纳入 2021 年 10 月至 2023 年 10 月安阳市人民医院收治的 82 例脑胶质瘤患者为研究样本,按随机单双数抽签法划分组别,41 例单数入对照组,予常规显微镜下脑肿瘤切除术治疗;另外 41 例双数者入研究组,予以荧光引导技术结合多模态影像神经导航脑肿瘤切除术治疗。对比两组手术指标(术中出血量、手术时间、住院时间)、治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、术后新发神经功能缺损发生情况,随访 1 年内肿瘤复发率。结果 研究组术中出血量低于对照组,手术时间、住院时间短于对照组,差异均有统计学意义(P<0。05);治疗前两组NIHSS评分对比差异无统计学意义(P>0。05),治疗后两组NIHSS评分均低于治疗前,且研究组评分低于对照组,差异均有统计学意义(P<0。05);研究组术后新发神经功能缺损发生率(4。88%)低于对照组(24。39%),差异具有统计学意义(P<0。05);研究组随访 1 年内肿瘤复发率(2。44%)低于对照组(14。63%),差异具有统计学意义(P<0。05)。结论 对比常规显微镜下脑肿瘤切除术,荧光引导技术结合多模态影像神经导航在脑胶质瘤中术中出血量更低、手术时间、住院时间更短,且有利于神经功能恢复,复发率较低,值得应用。
Application Effect of Fluorescence-Guided Technology Combined with Multimodal Image Neuro-navigation in Glioma
Objective To analyze the application effect of fluorescence-guided technology combined with multimodal image neuro-navigation in glioma and its impact on neurological function and tumor recurrence rate.Methods Eighty-two patients with glioma admitted to Anyang People's Hospital from October 2021 to October 2023 were included as the study sample.They were randomly divided into groups using a random odd-even number method,with 41 odd-numbered cases in the control group receiving conventional microscopic brain tumor resection,and 41 even-numbered cases in the study group receiving fluorescence-guided technology combined with multimodal image neuro-navigation brain tumor resection.Surgical indicators(intraoperative blood loss,operation time,hospital stay),NIH Stroke Scale(NIHSS)scores before and after treatment,incidence of new postoperative neurological deficits,and tumor recurrence rate within one year of follow-up were compared between the two groups.Results The intraoperative blood loss in the study group was lower than that in the control group,and the operation time and hospital stay were shorter than those in the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in NIHSS scores between the two groups before treatment(P>0.05).After treatment,the NIHSS scores in both groups were lower than before treatment,and the scores in the study group were lower than those in the control group,with statistically significant differences(P<0.05).The incidence of new postoperative neurological deficits in the study group(4.88%)was lower than that in the control group(24.39%),with statistically significant differences(P<0.05).The tumor recurrence rate within one year of follow-up in the study group(2.44%)was lower than that in the control group(14.63%),with statistically significant differences(P<0.05).Conclusion Compared with conventional microscopic brain tumor resection,fluorescence-guided technology combined with multimodal image neuro-navigation in glioma results in lower intraoperative blood loss,shorter operation time and hospital stay,and is beneficial for neurological function recovery with a lower recurrence rate,making it worthy of application.

fluorescence-guided technologymultimodal image neuro-navigationgliomaneurological functiontumor recurrence rate

韩秀鹏、梁洪磊、罗文凯、高安举

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安阳市人民医院 神经外科,河南 安阳 455000

荧光引导技术 多模态影像神经导航 脑胶质瘤 神经功能 肿瘤复发率

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(9)