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经鼻高流量湿化氧疗在Ⅰ型呼吸衰竭患者中的疗效分析

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目的 分析经鼻高流量湿化氧疗在Ⅰ型呼吸衰竭患者中的疗效分析。方法 将 2022 年 10 月至 2023 年 10 月南阳市中心医院 76 例Ⅰ型呼吸衰竭患者纳入为研究对象,依据随机单双数抽签法分组,38 例单数者入对照组,给予常规面罩吸氧支持;另外 38 例双数者入研究组,给予经鼻高流量湿化氧疗。对比两组治疗前后血气分析指标[动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、动脉血氧饱和度(SaO2)]、氧疗时间、重症监护室(ICU)住院时间、氧疗相关并发症发生率及治疗前后舒适度量表评分。结果 治疗前组间PaO2、PaCO2、SaO2 水平对比差异无统计学意义(P>0。05),治疗后两组PaO2、SaO2 水平高于治疗前,PaCO2 水平低于治疗前,且研究组PaO2、SaO2 水平高于对照组,PaCO2 水平低于对照组,差异均有统计学意义(P<0。05);研究组氧疗时间、ICU住院时间均短于对照组,差异均有统计学意义(P<0。05);研究组氧疗相关并发症发生率(5。26%)低于对照组(23。68%),差异具有统计学意义(P<0。05);治疗前组间舒适度量表评分对比差异无统计学意义(P>0。05),治疗后两组评分均高于治疗前,且研究组评分高于对照组,差异均有统计学意义(P<0。05)。结论 经鼻高流量湿化氧疗在Ⅰ型呼吸衰竭患者中的疗效更为理想,可显著改善动脉血气指标,缩短氧疗时间、住院时间,提高患者舒适度,降低氧疗相关并发症,值得临床应用。
Efficacy Analysis of High-Flow Nasal Cannula Oxygen Therapy in Patients with Type I Respiratory Failure
Objective To analyze the efficacy of high-flow nasal cannula oxygen therapy in patients with type I respiratory failure.Methods Seventy-six patients with type I respiratory failure admitted to Nanyang Central Hospital from October 2022 to October 2023 were included as study subjects.They were divided into groups using a random odd-even number method,with 38 odd-numbered cases in the control group receiving conventional mask oxygen support,and 38 even-numbered cases in the study group receiving High-flow nasal cannula oxygen therapy.Blood gas analysis indicators[partial pressure of arterial oxygen(PaO2),Partial Pressure of Carbon Dioxide(PaCO2),arterial oxygen saturation(SaO2)],oxygen therapy time,ICU stay duration,incidence of oxygen therapy-related complications,and comfort scale scores before and after treatment were compared between the two groups.Results There were no statistically significant differences in PaO2,PaCO2,and SaO2 levels between the groups before treatment(P>0.05).After treatment,PaO2 and SaO2 levels in both groups were higher than before treatment,and PaCO2 levels were lower than before treatment.The PaO2 and SaO2 levels in the study group were higher than those in the control group,and the PaCO2 level was lower than that in the control group,with statistically significant differences(P<0.05).The oxygen therapy time and ICU stay duration in the study group were shorter than those in the control group,with statistically significant differences(P<0.05).The incidence of oxygen therapy-related complications in the study group(5.26%)was lower than that in the control group(23.68%),with statistically significant differences(P<0.05).There were no statistically significant differences in comfort scale scores between the groups before treatment(P>0.05).After treatment,the comfort scale scores in both groups were higher than before treatment,and the scores in the study group were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion High-flow nasal cannula oxygen therapy is more effective in patients with type I respiratory failure,significantly improving arterial blood gas indicators,shortening oxygen therapy time and hospital stay,enhancing patient comfort,and reducing oxygen therapy-related complications,making it worthy of clinical application.

high-flow nasal cannula oxygen therapytype i respiratory failureoxygen therapy-related complicationsblood gas indicatorscomfort

周张瓅、周张玓、张雪

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南阳市中心医院 综合ICU,河南 南阳 473000

南阳市中心医院 神经外科三病区,河南 南阳 473000

经鼻高流量湿化氧疗 Ⅰ型呼吸衰竭 氧疗相关并发症 血气指标 舒适度

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(9)