Efficacy of Acupuncture Combined with Mouse Nerve Growth Factor in the Treatment of Peripheral Facial Paralysis in Children Based on Neuroelectrophysiological Changes
Objective To explore the clinical efficacy of acupuncture combined with mouse nerve growth factor in the treatment of peripheral facial paralysis in children based on neuroelectrophysiological changes.Methods Eighty-one children with peripheral facial paralysis admitted to The First Affiliated Hospital of Nanyang Medical College from April 2022 to March 2024 were randomly divided into a control group and a study group.The control group received conventional acupuncture treatment,while the study group received mouse nerve growth factor injections in addition to the conventional acupuncture treatment.Both groups were treated for 28 days.The facial nerve function,compound muscle action potential of the facial nerve,and traditional Chinese medicine syndrome scores before and after treatment were compared,and the clinical efficacy of the two groups was statistically analyzed.Results The treatment efficacy in the study group(97.56％)was higher than that in the control group(80.00％),with statistically significant differences(P<0.05).Before treatment,there were no statistically significant differences in traditional Chinese medicine syndrome scores,House-Brackmann facial nerve function grading(H-B grading),Portmann simplified scoring scale scores,and facial nerve electrophysiological detection results between the two groups(P>0.05).After treatment,the above indicators in both groups significantly improved,with the traditional Chinese medicine syndrome scores in the study group being significantly lower than those in the control group,with statistically significant differences (P<0.05). The H-B grading and Portmann scores in the study group improved more significantly,with statistically significant differences (P<0.05). Neuroelectrophysiological detection results showed that the incidence of abnormal compound muscle action potential (CMAP) and blink reflex (BR) detection in the study group was significantly lower than that in the control group,with statistically significant differences (P<0.05). The amplitudes of the facial nerve electromyography (ENoG) in the orbicularis oris muscle,nasalis muscle,and frontalis muscle in the study group were higher than those in the control group,with statistically significant differences (P<0.001). Conclusion Acupuncture combined with mouse nerve growth factor can effectively improve the neuroelectrophysiology,facial nerve function,and symptoms of children with peripheral facial paralysis. It has a significant effect on promoting the recovery of nerve function and is worthy of promotion and application.
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