Analysis of the Efficacy of Qili Qiangxin Capsules Combined with Recombinant Human Brain Natriuretic Peptide in the Treatment of Acute Heart Failure
Objective To investigate the clinical effect of recombinant human brain natriuretic peptide(rhBNP)combined with Qili Qiangxin capsules in the treatment of patients with acute heart failure(AHF).Methods Eighty-six AHF patients admitted to Suiping Ren'an Hospital from August 2020 to September 2023 were selected and divided into a study group(43 cases)and a control group(43 cases)using a random ball-drawing method.The control group received rhBNP treatment,while the study group received Qili Qiangxin capsules combined with rhBNP treatment.The clinical efficacy,cardiac function,TCM syndrome scores,and adverse reactions were compared between the two groups.Results The treatment efficacy in the study group(90.70%)was higher than that in the control group(74.42%),with statistically significant differences(P＜0.05).After treatment,the left ventricular ejection fraction(LVEF)increased,and the left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)decreased in both groups,with statistically significant differences(P＜0.05).The LVEF level in the study group was higher than that in the control group,and the LVESD and LVEDD levels were lower than those in the control group,with statistically significant differences(P＜0.05).After treatment,the TCM syndrome scores in both groups decreased,with statistically significant differences(P＜0.05),and the scores in the study group were lower than those in the control group,with statistically significant differences(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the study group(11.63%)and the control group(13.95%)(P＞0.05).Conclusion The combination of Qili Qiangxin capsules and rhBNP in the treatment of AHF patients can improve efficacy,enhance cardiac function,reduce TCM syndrome scores,and has high safety.
acute heart failureQili Qiangxin capsulesrecombinant human brain natriuretic peptideclinical efficacycardiac function
万方数据
维普
