首页|C反应蛋白与白介素-6联合血常规检验在老年COPD患者中的作用分析

C反应蛋白与白介素-6联合血常规检验在老年COPD患者中的作用分析

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目的 探究老年慢性阻塞性肺疾病(COPD)患者采取C反应蛋白(CRP)与白介素-6(IL-6)联合血常规作为检验方法的应用价值。方法 选取新乡市第二人民医院 2021 年 9 月至 2023 年 9 月收治的 41 例COPD患者作为实验组研究对象,另选取 41 例健康体检者作为对照组研究对象。对比两组血常规[中性粒细胞(NEU)、白细胞计数(WBC)、血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、血红蛋白(Hb)]、CRP、IL-6 检测结果。结果 实验组CRP、IL-6 水平均高于对照组,差异有统计学意义(P<0。05);实验组NEU、WBC、PLT、PDW、MPV、Hb水平高于对照组,差异有统计学意义(P<0。05);联合检查准确度、灵敏度、特异度高于单项检查,差异有统计学意义(P<0。05)。结论 CRP、IL-6 始终参与COPD炎性活动中,将上述两项指标与血常规检查联合实施可提升COPD诊断精确性,值得应用。
Analysis of the Role of Combined Testing of C-Reactive Protein and Interleukin-6 with Routine Blood Tests in Elderly COPD Patients
Objective To explore the application value of using C-reactive protein(CRP)and interleukin-6(IL-6)combined with routine blood tests as a testing method in elderly patients with chronic obstructive pulmonary disease(COPD).Methods A total of 41 COPD patients admitted to The Second People's Hospital of Xinxiang from September 2021 to September 2023 were selected as the experimental group,and 41 healthy individuals undergoing physical examinations were selected as the control group.The results of routine blood tests[neutrophils(NEU),white blood cell count(WBC),platelet count(PLT),mean platelet volume(MPV),platelet distribution width(PDW),hemoglobin(Hb)],CRP,and IL-6 were compared between the two groups.Results The levels of CRP and IL-6 in the experimental group were higher than those in the control group,with statistically significant differences(P<0.05).The levels of NEU,WBC,PLT,PDW,MPV,and Hb in the experimental group were higher than those in the control group,with statistically significant differences(P<0.05).The accuracy,sensitivity,and specificity of the combined tests were higher than those of single tests,with statistically significant differences(P<0.05).Conclusion CRP and IL-6 are consistently involved in the inflammatory activities of COPD.Combining these two indicators with routine blood tests can improve the accuracy of COPD diagnosis and is worth applying.

Routine blood testsC-reactive proteinInterleukin-6Chronic obstructive pulmonary disease

王素玲

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新乡市第二人民医院 检验科,河南 新乡 453000

血常规 C反应蛋白 白介素6 慢性阻塞性肺疾病

2024

临床研究
西安交通大学

临床研究

影响因子:0.234
ISSN:2096-1278
年,卷(期):2024.32(9)