Effect of Caprini Venous Thromboembolism Risk Assessment Guiding Low Molecular Weight Heparin in Pregnant Women and Its Role in the Prevention and Treatment of Venous Thrombosis
Objective To explore the effect of Caprini venous thromboembolism(VTE)risk assessment guiding low molecular weight heparin in pregnant women and its role in the prevention and treatment of venous thrombosis.Methods A total of 200 pregnant women with VTE risk admitted to Shunde Hospital,Affiliated to Jinan University,from January 2022 to April 2023 were selected and randomly divided into an observation group and a control group,with 100 cases in each group.The control group was managed according to the previous patient management strategies of the department,while the observation group strictly used the Caprini model to assess and grade VTE risk and took corresponding measures.Clinical data,including age,body mass index,number of pregnancies,hypertension,diabetes,family history of VTE,C-reactive protein(CRP),and platelet count(PLT),were compared between the two groups.The incidence of VTE during pregnancy,within 3 months postpartum,and within 12 months postpartum,as well as the incidence of bleeding complications,were recorded and compared.The quality of life of high-risk pregnant women was assessed using the European Quality of Life 5 Dimensions 3 Level Version(EQ-5D-3L)during pregnancy,at 3 months postpartum,and at 12 months postpartum.Results There was no statistically significant difference in the incidence of VTE during pregnancy,within 3 months postpartum,and within 12 months postpartum between the two groups(P＞0.05).There was no statistically significant difference in the incidence of bleeding complications during pregnancy between the two groups(P＞0.05).The incidence of bleeding complications within 3 months postpartum and within 12 months postpartum in the observation group was lower than that in the control group,with statistically significant differences(P＜0.05).The EQ-5D-3L scores of high-risk pregnant women in the observation group were(6.11±1.05)during pregnancy,(8.09±1.37)at 3 months postpartum,and(9.13±0.52)at 12 months postpartum.The differences in EQ-5D-3L scores at different time points were statistically significant(P＜0.05).The EQ-5D-3L scores at 3 months and 12 months postpartum in the observation group were higher than those in the control group,with statistically significant differences(P＜0.05).Conclusion The Caprini risk assessment model can prevent the occurrence of VTE,reduce the incidence of bleeding complications,and improve the quality of life postpartum.
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